How Do You Spell PEPTIDE NUCLEIC ACIDS?

Pronunciation: [pˈɛpta͡ɪd njuːklˈɪɪk ˈasɪdz] (IPA)

Peptide Nucleic Acids (PNAs) is a term in molecular biology that refers to a synthetic analog of DNA that is composed of repeating N-(2-aminoethyl) glycine units. The correct spelling of this term can be explained phonetically using the International Phonetic Alphabet (IPA) as /pɛptɪd njukliɪk ˈæsɪdz/. The stress falls on the second syllable of each word, and the pronunciation of the word "peptide" is similar to "pep-tide" with a short "e" sound. The pronunciation of "nucleic" has a long "u" sound and the "c" is pronounced as an "s".

PEPTIDE NUCLEIC ACIDS Meaning and Definition

  1. Peptide Nucleic Acids (PNAs) are synthetic analogs of naturally occurring nucleic acids such as DNA and RNA, but with an altered chemical backbone. They are composed of repeating units of N-(2-aminoethyl)-glycine, also known as aminoethyl glycine or aeg, which replaces both the sugar and phosphate backbone found in DNA and RNA. This chemical modification provides PNAs with unique properties, such as enhanced stability, increased binding affinity to target nucleic acids, and resistance to degradation by various cellular enzymes.

    PNAs can bind to complementary DNA or RNA sequences through Watson-Crick base pairing to form PNA-DNA or PNA-RNA complexes. This binding allows PNAs to modulate gene expression by preventing the binding of other molecules, such as transcription factors or enzymes, to the target sequence. It can also inhibit the activity of specific RNA molecules by interfering with their function.

    Due to their ability to specifically bind to DNA or RNA targets, PNAs have shown great potential in several fields, including molecular biology, diagnostics, and therapeutics. They can be used as tools in various molecular biology techniques, such as PCR (Polymerase Chain Reaction) and DNA sequencing. In diagnostics, PNAs can be employed to detect and identify specific DNA or RNA sequences, acting as probes for genetic tests. In therapeutics, PNAs have been investigated as potential antisense agents to target and silence disease-causing genes, with the aim of developing novel treatments for genetic disorders, viral infections, and even cancer.

    Overall, Peptide Nucleic Acids represent a unique class of synthetic nucleic acids that offer versatile applications and hold promise for future advancements in genomics and medicine.

Common Misspellings for PEPTIDE NUCLEIC ACIDS

  • oeptide nucleic acids
  • leptide nucleic acids
  • -eptide nucleic acids
  • 0eptide nucleic acids
  • pwptide nucleic acids
  • psptide nucleic acids
  • pdptide nucleic acids
  • prptide nucleic acids
  • p4ptide nucleic acids
  • p3ptide nucleic acids
  • peotide nucleic acids
  • peltide nucleic acids
  • pe-tide nucleic acids
  • pe0tide nucleic acids
  • pepride nucleic acids
  • pepfide nucleic acids
  • pepgide nucleic acids
  • pepyide nucleic acids
  • pep6ide nucleic acids
  • pep5ide nucleic acids

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