PEPTIDE LINKAGE Meaning and
Definition
-
A peptide linkage, also known as an amide linkage, is a specific type of covalent chemical bond that forms between two amino acids during the process of protein synthesis. It is an essential component of proteins and plays a critical role in their structure and function.
A peptide linkage is formed through a condensation reaction, where the carboxyl group (-COOH) of one amino acid reacts with the amino group (-NH2) of another amino acid, resulting in the release of a water molecule. This reaction is catalyzed by enzymes known as ribosomes.
The resulting bond is called a peptide bond and is characterized by the formation of a rigid planar structure due to the presence of a double bond between the carbon and nitrogen atoms. It is this peptide bond that links multiple amino acids together, forming a chain or "polymer" known as a polypeptide.
Peptide linkages are crucial for maintaining protein structure and function. They contribute to the secondary and tertiary structures of proteins, such as the alpha helices and beta sheets, by dictating the folding patterns of the polypeptide chain. Additionally, peptide linkages are involved in protein stability, enzymatic activity, and molecular recognition processes.
Understanding the nature and properties of peptide linkages is important in various fields including biochemistry, molecular biology, and medicine, as it provides insights into the structure-function relationship of proteins and aids in the design of pharmaceutical drugs and therapeutic interventions.
Common Misspellings for PEPTIDE LINKAGE
- oeptide linkage
- leptide linkage
- -eptide linkage
- 0eptide linkage
- pwptide linkage
- psptide linkage
- pdptide linkage
- prptide linkage
- p4ptide linkage
- p3ptide linkage
- peotide linkage
- peltide linkage
- pe-tide linkage
- pe0tide linkage
- pepride linkage
- pepfide linkage
- pepgide linkage
- pepyide linkage
- pep6ide linkage
Etymology of PEPTIDE LINKAGE
The word "peptide" originates from the Greek term "peptos", which means "digested" or "dissolved". This term was coined by the German physiologist and chemist, Theodor Curtius, in 1902. The word "linkage" is derived from the Old English word "linca", meaning "a band or chain". Thus, the term "peptide linkage" refers to the connection or bond between two amino acids in a peptide chain, forming a peptide bond.
Similar spelling word for PEPTIDE LINKAGE
Infographic
Add the infographic to your website:
