How Do You Spell PENICILLIN G ACYLASE?

Pronunciation: [pˈɛnɪsˌɪlɪn d͡ʒˈiː ɐkˈɪle͡ɪs] (IPA)

The word "penicillin G acylase" is spelled using the International Phonetic Alphabet (IPA) symbols. "Penicillin" is pronounced as /pɛnɪˈsɪlɪn/, with the stress on the second syllable. "G" is pronounced as /dʒiː/. "Acylase" is pronounced as /əˈsaɪleɪs/, with the stress on the second syllable. The word refers to an enzyme that catalyzes the hydrolysis of penicillin G, a type of antibiotic. The correct spelling of this word is important in scientific research and medical terminology.

PENICILLIN G ACYLASE Meaning and Definition

1. Penicillin G Acylase is an enzyme that belongs to the class of hydrolases, specifically those acting on carboxylic ester bonds. It is primarily involved in the hydrolysis of the amide bond between the acyl side chain of penicillin G and the amino acid moiety, resulting in the formation of the corresponding penicilloic acid. This enzyme is widely utilized in industrial processes for the production of semi-synthetic β-lactam antibiotics.

   Penicillin G Acylase is an important biocatalyst in the pharmaceutical industry due to its ability to convert penicillin G, a natural antibiotic produced by the fungus Penicillium notatum, into various derivatives with enhanced or modified antibacterial properties. By cleaving the acyl side chain, this enzyme facilitates the production of semi-synthetic penicillins, such as ampicillin and amoxicillin, which exhibit expanded antibacterial spectra and increased resistance to penicillinase enzymes.

   In addition to its role in the production of antibiotics, Penicillin G Acylase finds application in the food industry for the production of low-calorie, high-intensity sweeteners. By enzymatically modifying specific amino acids, this enzyme can convert inexpensive substrates into valuable sweeteners, such as aspartame.

   Overall, Penicillin G Acylase is a versatile enzyme with significant industrial importance. Its ability to catalyze the hydrolysis of penicillin G and key amino acid modifications has paved the way for the development of various semi-synthetic antibiotics and sweeteners, contributing to the advancement of pharmaceutical and food manufacturing processes.

Common Misspellings for PENICILLIN G ACYLASE

• oenicillin g acylase
• lenicillin g acylase
• -enicillin g acylase
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