Opsonophilia is a medical term used to describe an increased attraction of phagocytes to opsonized particles. This term is derived from two Greek words, "opsonē" meaning "food" and "philia" meaning "love" or "liking". It is spelled as /ɒpsənəˈfɪliə/ in IPA phonetic transcription, where the "o" is pronounced as "ah", and the "e" in both "opsonē" and "philia" is pronounced as "ee." The emphasis is on the second syllable, and the final "a" in "philia" is silent.
Opsonophilia is a term used in immunology to describe a condition characterized by an excessive attraction or affinity towards opsonins. Opsonins are molecules that enhance the process of phagocytosis, which is the engulfment and destruction of foreign particles or pathogens by white blood cells called phagocytes.
In the immune system, opsonins act as a bridge between phagocytes and the target particles, such as bacteria or viruses. They enhance the recognition and binding of phagocytes to these particles, thereby facilitating their elimination. Opsonophilia refers to an abnormal increase in the production, release, or activity of opsonins, leading to an enhanced immune response.
Individuals with opsonophilia may show symptoms of heightened immune responses, including increased inflammation, more efficient pathogen clearance, and reduced susceptibility to infections. However, excessive opsonin activity can also result in immune system dysregulation, leading to autoimmune disorders or chronic inflammation.
The term "opsonophilia" is derived from the Greek words "opson," meaning preparation or seasoning, and "philia," meaning love or attraction. It emphasizes the exaggerated affinity towards opsonins observed in this condition.
Opsonophilia can be measured by analyzing blood samples for opsonin levels, or by determining the activity of opsonins in promoting phagocytosis. Understanding the mechanisms and implications of opsonophilia can provide insights into immune system function, as well as potential therapeutic strategies for regulating immune responses in various diseases.
The condition in which bacteria readily unite with opsonins, rendering them a prey to phagocytosis.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "opsonophilia" is a combination of two Greek terms: "opson", meaning "relish" or "appetizing food", and "philia", meaning "a liking" or "an attraction". The term is derived from the ancient Greek practice of opson, which involved adding sauces or spices to enhance the flavor of food. In a broader sense, opsonophilia refers to a strong fondness or preference for appetizing or tasty food.