NGFR PROTEIN Meaning and
Definition
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The NGFR protein, also known as the Nerve Growth Factor Receptor, is a transmembrane protein that plays a crucial role in signaling pathways related to neuronal development, survival, and differentiation. It belongs to the tumor necrosis factor receptor superfamily and is primarily expressed in neurons and certain peripheral tissues.
The NGFR protein functions as a receptor for the nerve growth factor (NGF), a neurotrophic factor essential for the growth, survival, and maintenance of neurons in the central and peripheral nervous systems. Upon binding to NGF, the NGFR protein undergoes conformational changes and activates downstream signaling cascades, ultimately leading to cellular responses, such as neurite outgrowth, neuronal survival, and differentiation.
In addition to its role in neuronal development, NGFR has also been implicated in other physiological processes such as immune response, inflammation, and cancer progression. It is involved in modulating immune cell signaling and contributes to the regulation of several immune responses.
Dysregulation of NGFR and its signaling pathways has been associated with various neurological disorders, including neurodegenerative diseases and neuropathic pain conditions. On the other hand, targeting NGFR has emerged as a potential therapeutic strategy for neuroprotection and nerve regeneration in the treatment of neurodegenerative diseases, nerve injuries, and chronic pain.
In summary, the NGFR protein is a transmembrane receptor that plays a vital role in neuronal development, survival, and differentiation. It is involved in multiple physiological processes and emerges as a potential therapeutic target for various neurological disorders.
Common Misspellings for NGFR PROTEIN
- bgfr protein
- mgfr protein
- jgfr protein
- hgfr protein
- nffr protein
- nvfr protein
- nbfr protein
- nhfr protein
- nyfr protein
- ntfr protein
- ngdr protein
- ngcr protein
- ngvr protein
- nggr protein
- ngtr protein
- ngrr protein
- ngfe protein
- ngfd protein
- ngff protein
- ngft protein
Etymology of NGFR PROTEIN
The etymology of the word "NGFR protein" can be broken down as follows:
1. NGFR: NGFR stands for Nerve Growth Factor Receptor. The term "nerve growth factor" refers to a protein that is important for the growth and survival of nerve cells. The receptor is a specific protein on the cell surface that binds to the nerve growth factor, allowing the cell to respond to its signals. The term "nerve growth factor receptor" was coined to describe this specific protein that mediates the effects of nerve growth factor.
2. Protein: The term "protein" is derived from the French word "protéine", which was coined in 1838 by the Swedish chemist Jöns Jacob Berzelius. It is derived from the Greek word "protos", meaning "first rank" or "primary", as proteins were considered the most important components of living matter.
