How Do You Spell NADH DEHYDROGENASE?

Pronunciation: [nˈad dˌiːha͡ɪdɹˈə͡ʊd͡ʒne͡ɪs] (IPA)

NADH Dehydrogenase, also known as Complex I, is an important protein complex in the electron transport chain. Its pronunciation can be explained using the International Phonetic Alphabet (IPA): /'ɛn-eɪ-diː-eɪtʃ/ /dih-haɪ-druh-juh-neys/. The "N" is pronounced like the letter "en." The "A" in "NADH" is pronounced like the letter "ay." "Dehydrogenase" is pronounced with the emphasis on the "ro" and "genase" is pronounced with a "juh" sound. Understanding the phonetic transcription can help with proper pronunciation in scientific contexts.

NADH DEHYDROGENASE Meaning and Definition

1. NADH dehydrogenase, also known as Complex I, is an enzyme complex located in the inner mitochondrial membrane of eukaryotic cells and the plasma membrane of prokaryotes. It plays a crucial role in oxidative phosphorylation, the process by which cells generate energy.

   The primary function of NADH dehydrogenase is to catalyze the transfer of electrons from NADH to ubiquinone, a mobile electron carrier molecule. This process generates a proton gradient across the membrane, which is used to produce adenosine triphosphate (ATP), the energy currency of the cell.

   Structurally, NADH dehydrogenase is a large protein complex composed of multiple subunits. These subunits work collaboratively to bind NADH and ubiquinone, catalyze the transfer of electrons, and pump protons across the membrane. The complex is also responsible for preventing the leakage of electrons and the production of harmful reactive oxygen species.

   NADH dehydrogenase is present in all aerobic organisms and is involved in various cellular processes, including cell respiration and metabolism. Dysfunction or mutations in this enzyme complex can lead to a variety of diseases, such as mitochondrial disorders and neurodegenerative conditions like Parkinson's disease.

   In summary, NADH dehydrogenase is an enzyme complex that plays a pivotal role in cellular respiration by catalyzing the transfer of electrons from NADH to ubiquinone, while also generating a proton gradient necessary for ATP synthesis.

Common Misspellings for NADH DEHYDROGENASE

• badh dehydrogenase
• madh dehydrogenase
• jadh dehydrogenase
• hadh dehydrogenase
• nzdh dehydrogenase
• nsdh dehydrogenase
• nwdh dehydrogenase
• nqdh dehydrogenase
• nash dehydrogenase
• naxh dehydrogenase
• nach dehydrogenase
• nafh dehydrogenase
• narh dehydrogenase
• naeh dehydrogenase
• nadg dehydrogenase
• nadb dehydrogenase
• nadn dehydrogenase
• nadj dehydrogenase
• nadu dehydrogenase
• nady dehydrogenase

Etymology of NADH DEHYDROGENASE

The word "NADH dehydrogenase" is a compound term that combines "NADH" and "dehydrogenase".

1. NADH: The acronym "NADH" stands for "nicotinamide adenine dinucleotide (NAD) + hydrogen (H)". It is a coenzyme involved in various biological reactions, primarily as an electron carrier in cellular respiration. The term "NADH" originated from its chemical composition, which includes a nicotinamide base, an adenine base, and a ribose sugar, along with the hydrogens it carries.

2. Dehydrogenase: The suffix "-dehydrogenase" indicates an enzyme that facilitates the removal of hydrogen atoms (dehydrogenation) from a molecule. This process is often coupled with the transfer of the removed electrons to an electron acceptor.