NADH, short for Nicotinamide Adenine Dinucleotide Hydride, is a coenzyme that plays a crucial role in cellular energy metabolism. It is a reduced form of NAD+ (Nicotinamide Adenine Dinucleotide) and serves as an electron carrier during various enzymatic reactions, particularly in the process of cellular respiration.
NADH is generated during the breakdown of carbohydrates, proteins, and fatty acids in the citric acid cycle and glycolysis. It serves as a crucial electron donor in the electron transport chain, which is an essential step in oxidative phosphorylation to produce ATP, the energy currency of cells. Through a series of redox reactions, NADH transfers its high-energy electrons to the electron transport chain, ultimately leading to the synthesis of ATP.
In addition to its role in energy production, NADH also serves as a cofactor for several important enzymes involved in the synthesis and repair of DNA. It participates in various metabolic pathways, including the metabolism of amino acids, fatty acids, and cholesterol.
Due to its involvement in energy production and various metabolic processes, NADH has garnered interest as a dietary supplement for its potential health benefits. It is believed to enhance energy levels, support cognitive function, and exhibit antioxidant properties. However, further research is needed to fully understand its effectiveness and implications for human health.
