The spelling of the word "most obliquitous" may seem daunting at first glance, but it's actually fairly straightforward when broken down phonetically. "Most" is pronounced /moʊst/, with a long "o" sound and a "st" ending. "Obliquitous" is pronounced /ɑbˈlɪkwətəs/, with emphasis on the second syllable and a silent "e" at the end. Together, the phrase is pronounced /moʊst ɑbˈlɪkwətəs/. While not commonly used in everyday conversation, it means "most inclined or inclined at an angle."