MONOGENIC DISORDER Meaning and
Definition
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Monogenic disorder is a term used in genetics to describe a type of genetic disorder that is caused by a single gene mutation or alteration. It is a hereditary condition that is inherited from one or both parents who carry the mutated gene.
In monogenic disorders, a specific gene is responsible for causing the disease or condition. These disorders can be inherited in various patterns, including autosomal dominant inheritance (where only one copy of the mutated gene is needed to cause the disorder), autosomal recessive inheritance (where both copies of the gene need to be mutated to cause the disorder), or X-linked inheritance (where the mutated gene is located on the X chromosome).
The symptoms and severity of monogenic disorders can vary widely, and they can affect different organ systems or parts of the body depending on the specific gene that is affected. Some examples of monogenic disorders include cystic fibrosis, sickle cell disease, Huntington's disease, and muscular dystrophy.
Diagnosis of monogenic disorders often involves genetic testing, which can help identify the specific gene mutation responsible for the disorder. This knowledge can be important for understanding the disease, predicting potential complications, and guiding treatment strategies. Genetic counseling may also be recommended to assess the risk of passing on the disorder to future generations.
Common Misspellings for MONOGENIC DISORDER
- nonogenic disorder
- konogenic disorder
- jonogenic disorder
- minogenic disorder
- mknogenic disorder
- mlnogenic disorder
- mpnogenic disorder
- m0nogenic disorder
- m9nogenic disorder
- mobogenic disorder
- momogenic disorder
- mojogenic disorder
- mohogenic disorder
- monigenic disorder
- monkgenic disorder
- monlgenic disorder
- monpgenic disorder
- mon0genic disorder
- mon9genic disorder
Etymology of MONOGENIC DISORDER
The word "monogenic" originates from the combination of two Greek roots: "mono" meaning "one" and "genos" meaning "race" or "kind". "Monogenic" refers to a trait or disorder caused by a single gene or genetic variant.
The term "disorder" comes from the Old French word "desordre", which originated from the Latin "dis-" meaning "apart" or "away" and "ordo" meaning "order" or "arrangement". In this context, "disorder" refers to a condition involving a disruption or abnormality in the regular functioning or structure of the body.
When combined, the term "monogenic disorder" refers to a specific type of disorder or disease that is caused by a single gene mutation or variant, leading to abnormal development or functioning of an organism.
Similar spelling word for MONOGENIC DISORDER
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