MOLONEY SARCOMA VIRUS Meaning and
Definition
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The Moloney Sarcoma Virus, also known as Mo-MuLV (Moloney murine leukemia virus), is a retrovirus belonging to the family of oncoviruses. It is a closely related variant of the Moloney murine sarcoma virus and was first discovered in the 1960s by Howard Temin and David Baltimore.
The Moloney Sarcoma Virus is primarily found in mice and has been extensively studied as a model for retroviral replication and oncogenesis. It is responsible for causing various forms of sarcoma and leukemia in infected mice. The virus induces the abnormal growth of cells by integrating its genetic material, specifically its RNA genome, into the host DNA, leading to uncontrolled cell division and tumor formation.
The Moloney Sarcoma Virus is classified as a type C retrovirus, characterized by its unique morphology and replication process. It possesses an outer envelope composed of lipids derived from the host cell membrane, surrounding an inner core that contains the viral RNA genome and viral proteins required for replication.
Research on the Moloney Sarcoma Virus has contributed significantly to the understanding of retroviral replication, reverse transcription, and the role of oncogenes in cancer development. It has served as a crucial tool for studying the molecular mechanisms of viral-induced oncogenesis and has paved the way for the development of antiretroviral therapies and vaccines targeting retroviruses and related oncogenic viruses.
Common Misspellings for MOLONEY SARCOMA VIRUS
- noloney sarcoma virus
- koloney sarcoma virus
- joloney sarcoma virus
- miloney sarcoma virus
- mkloney sarcoma virus
- mlloney sarcoma virus
- mploney sarcoma virus
- m0loney sarcoma virus
- m9loney sarcoma virus
- mokoney sarcoma virus
- moponey sarcoma virus
- moooney sarcoma virus
- moliney sarcoma virus
- molkney sarcoma virus
- mollney sarcoma virus
- molpney sarcoma virus
- mol0ney sarcoma virus
- mol9ney sarcoma virus
- molobey sarcoma virus
- molomey sarcoma virus
