MMTV Meaning and
Definition
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MMTV is an acronym that stands for Mouse Mammary Tumor Virus. It refers to a retrovirus that affects mice and has been extensively studied due to its ability to induce mammary gland tumors in the host. MMTV belongs to the retroviridae family, specifically the genus Betaretrovirus, and is classified as an oncogenic virus.
This virus is transmitted vertically from mother to offspring through milk, and occasionally horizontally between individuals, especially under stressful conditions. MMTV infects the mammary gland cells of mice and integrates its viral DNA into the host genome, which can result in the activation of cellular oncogenes and the development of mammary tumors in infected animals.
The study of MMTV has helped researchers better understand the mechanisms of viral infection and tumorigenesis. It has been extensively used as a model system to investigate the relationship between viruses and cancer development. MMTV has also aided in the discovery and characterization of various viral oncogenes that contribute to cancer progression.
Furthermore, MMTV has provided insights into potential routes of cancer transmission among species, as it shares similarities with viruses that infect humans, such as the human mammary tumor virus (HMTV). Understanding the behavior and mechanisms of MMTV infection has wider implications in the study of viral oncogenesis, ultimately contributing to advancements in cancer research and prevention strategies.
Common Misspellings for MMTV
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