Metribolone, also known by its brand name Methyltrienolone or R1881, is a synthetic androgen and anabolic steroid. It falls under the class of 17α-alkylated androgens, meaning it has a structural modification at the 17th carbon position to enhance its oral bioavailability.
Metribolone is highly potent, characterized by its strong androgenic and anabolic effects. It was initially developed for veterinary use, specifically for promoting weight gain, muscle mass, and appetite in animals. However, due to its potency, it has gained popularity among bodybuilders and athletes seeking enhanced performance and physique enhancement.
This compound binds to and activates the androgen receptor, leading to increased protein synthesis, nitrogen retention, and stimulation of muscle growth. Metribolone is known for its ability to rapidly increase strength and muscle mass, which has made it attractive for those looking to achieve significant gains in a short period of time.
It is important to note that due to its high anabolic potency, metribolone is associated with several side effects. These can include liver toxicity, suppression of natural testosterone production, mood changes, aggression, and cardiovascular issues. Additionally, its potent androgenic nature may result in virilization symptoms in women including deepening of the voice, clitoral enlargement, and excessive hair growth.
Metribolone is recognized as a potent and potentially dangerous compound, therefore it is classified as a controlled substance and is illegal for human use in many countries. It should only be taken under strict medical supervision and guidance.
