How Do You Spell MEGAKARYOCYTES?

Pronunciation: [mˌɛɡəkˈaɹɪəsˌa͡ɪts] (IPA)

Megakaryocytes is a medical term used to refer to large cells that produce platelets in the bone marrow. The word is pronounced /ˌmɛɡəˈkæriəˌsaɪts/ using the International Phonetic Alphabet (IPA). The first syllable, "mega," is pronounced with a short "e" sound, followed by the stress falling on the second syllable, "karyo," which is pronounced with a long "a" sound. Finally, the word ends with the suffix "-cytes," pronounced with a short "i" sound followed by a "t" and "s" sound. Overall, the spelling of "Megakaryocytes" reflects the pronunciation of the individual sounds in the word.

MEGAKARYOCYTES Meaning and Definition

1. Megakaryocytes are large cells found in the bone marrow and are responsible for the production of platelets. They are categorized as a type of hematopoietic (blood-forming) cell and are derived from multipotent stem cells in a process called megakaryopoiesis.

   These cells are characterized by their unique appearance, as they are much larger than most other cells found in the bone marrow. Megakaryocytes feature a large irregular-shaped nucleus and abundant cytoplasm, which contains various structures known as demarcation membranes that eventually develop into platelets.

   During megakaryopoiesis, the megakaryocyte undergoes a complex maturation process that involves DNA replication without cell division, leading to the formation of multiple lobes in the nucleus. As the megakaryocyte matures, cytoplasmic extensions known as proplatelets begin to form. These proplatelets extend into the sinusoids, the blood vessels within the bone marrow, where platelets shed from the tips.

   Once released into the bloodstream, platelets play a crucial role in the process of hemostasis, which is the body's mechanism to prevent blood loss when a blood vessel is damaged. Platelets adhere to the site of injury and aggregate together, forming a plug to seal the damaged vessel.

   Understanding the biology and function of megakaryocytes is important in the context of various diseases and disorders, including thrombocytopenia (low platelet count) and various myeloproliferative neoplasms where megakaryocyte proliferation is increased.

Common Misspellings for MEGAKARYOCYTES

• negakaryocytes
• kegakaryocytes
• jegakaryocytes
• mwgakaryocytes
• msgakaryocytes
• mdgakaryocytes
• mrgakaryocytes
• m4gakaryocytes
• m3gakaryocytes
• mefakaryocytes
• mevakaryocytes
• mebakaryocytes
• mehakaryocytes
• meyakaryocytes
• metakaryocytes
• megzkaryocytes
• megskaryocytes
• megwkaryocytes
• megqkaryocytes
• megajaryocytes

Etymology of MEGAKARYOCYTES

The word "megakaryocytes" is derived from two Greek words: "mega" meaning large and "karyon" meaning nucleus. In medical terminology, "cytes" is a suffix used to refer to cells. Therefore, "megakaryocytes" literally translates to "large nuclear cells". This term was chosen due to the large size of the nucleus found in these cells. Megakaryocytes are responsible for the production of platelets in the bone marrow.