LYSYL OXIDASE Meaning and
Definition
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Lysyl oxidase is an enzyme that plays a crucial role in the process of collagen and elastin cross-linking, which is essential in maintaining the structural integrity and functionality of various connective tissues in the body. It belongs to the family of copper-dependent amine oxidases and is primarily responsible for catalyzing the oxidative deamination of lysine residues in collagen and elastin proteins.
This enzyme is involved in extracellular matrix remodeling and is implicated in numerous physiological and pathological processes. Lysyl oxidase works by generating reactive aldehyde groups in the collagen and elastin molecules, which then react with neighboring lysine residues to form cross-links, increasing the stability and elasticity of these protein structures.
The activity of lysyl oxidase is tightly regulated to prevent excessive cross-linking, as abnormal levels of collagen and elastin cross-linking can lead to tissue stiffness and loss of function. Dysregulation of lysyl oxidase has been linked to various pathological conditions, including fibrosis, cardiovascular diseases, and cancer metastasis.
Understanding the function and regulation of lysyl oxidase is of great importance in medical research and drug development, as targeting this enzyme may offer potential therapeutic strategies for diseases associated with abnormal tissue remodeling.
Common Misspellings for LYSYL OXIDASE
- kysyl oxidase
- pysyl oxidase
- oysyl oxidase
- ltsyl oxidase
- lgsyl oxidase
- lhsyl oxidase
- lusyl oxidase
- l7syl oxidase
- l6syl oxidase
- lyayl oxidase
- lyzyl oxidase
- lyxyl oxidase
- lydyl oxidase
- lyeyl oxidase
- lywyl oxidase
- lystl oxidase
- lysgl oxidase
- lyshl oxidase
- lysul oxidase
- lys7l oxidase
Etymology of LYSYL OXIDASE
The word "Lysyl Oxidase" has its roots in scientific nomenclature and is derived from the combination of "lysin" and "oxidase".
- "Lysin" refers to lysine, which is an amino acid. The term "lysine" itself comes from the Greek word "lysīs", meaning "to loosen, release, or dissolve", suggesting the property of breaking down or altering proteins.
- "Oxidase" refers to an enzyme that catalyzes oxidation reactions. The term "oxidase" has its origins in the Latin word "oxis", meaning "acid", and the Greek word "hodos", meaning "way" or "path". Combined, it indicates the enzyme's ability to facilitate oxidative reactions.
