Lupus hypertrophicus is a medical term used to describe a rare, chronic skin disorder characterized by the development of thickened, hardened, and hypertrophic patches on the skin, typically in individuals affected by systemic lupus erythematosus (SLE). This condition is considered a cutaneous manifestation of SLE, an autoimmune disease that can affect various organs and tissues in the body.
Lupus hypertrophicus primarily affects the skin, especially areas that are commonly exposed to sunlight, such as the face, neck, and arms. The skin lesions associated with this condition are characterized by thickened, firm, and raised plaques that may appear red or skin-colored. Over time, the patches can become scaly, hyperpigmented, and may cause itching or discomfort.
The exact cause of lupus hypertrophicus is unknown, but it is believed to be due to the abnormal immune response seen in SLE. The skin lesions arise as a result of the deposition of immune complexes, inflammation, and altered cellular processes. Other factors, such as genetics, hormonal balance, and environmental triggers, may also contribute to the development of lupus hypertrophicus.
Treatment for lupus hypertrophicus primarily involves managing the underlying SLE through medications, such as corticosteroids, immunosuppressants, and antimalarial drugs, to control the immune system. Additionally, topical treatments, such as corticosteroid creams and ointments, may be prescribed to alleviate symptoms and reduce the appearance of the skin lesions. Photoprotective measures, such as wearing sunscreen and avoiding excessive sun exposure, are essential to prevent further damage to the skin. In some cases, laser therapy or surgical removal of the lesions may be considered to improve cosmetic outcomes. Regular monitoring by a
