Liver cell adenomas are benign tumors that develop in the liver, originating from the cells that make up the liver tissue, specifically the hepatocytes. These adenomas are typically solitary, although multiple adenomas can occur simultaneously. Liver cell adenomas are usually non-cancerous and do not spread to other parts of the body.
Liver cell adenomas can vary in size, ranging from small lesions to large masses, and are typically round or oval in shape. They are typically well-demarcated and encapsulated. Although the majority of liver cell adenomas do not cause any symptoms, they can occasionally present with abdominal pain, particularly if they become large in size or rupture.
The exact cause of liver cell adenomas is not well understood, but they are believed to be hormone-related, as they are more common in women who are of childbearing age and are often associated with the use of oral contraceptives. Additionally, liver cell adenomas can be related to underlying liver diseases such as glycogen storage disease or familial adenomatous polyposis.
Although liver cell adenomas are usually benign, there is a small risk of complications. The most concerning complication is the potential for rupture, which can cause severe pain, internal bleeding, and even life-threatening hemorrhage. In rare cases, liver cell adenomas can also undergo malignant transformation into hepatocellular carcinoma.
Treatment options for liver cell adenomas depend on various factors, including the size of the adenoma, presence of symptoms, risk of rupture, and potential for malignant transformation. Conservative management, including close monitoring and discontinuation of oral contraceptives, may be appropriate for small, asymptomatic adenomas. However, in cases where the risk of rupture or malignancy is high, surgical intervention may be recommended, which can involve removal of the aden
