LEVORIN Meaning and
Definition
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Levorin is a potent antifungal agent that belongs to the polyene class of antibiotics. It is derived from Streptomyces lividans and is commonly used in the treatment of fungal infections, particularly those caused by Candida species.
Levorin works by binding to the fungal cell membrane and creating pores or channels that disrupt the integrity and function of the membrane. This ultimately leads to the leakage of essential cellular components and the death of the fungal cells. Levorin exhibits broad-spectrum activity against various Candida species, including Candida albicans and Candida tropicalis, which are associated with infections such as oral thrush, skin and nail infections, and systemic candidiasis.
As a polyene antibiotic, levorin has a characteristic structure consisting of a large ring structure with multiple conjugated double bonds. This structural feature allows it to interact with fungal cell membranes, specifically targeting the ergosterol component present in fungal membranes. Ergosterol is essential for the integrity and function of the fungal cell membrane, and levorin's interaction with it disrupts membrane function, leading to cell death.
Levorin is typically administered topically in the form of creams, ointments, or powders for localized fungal infections. However, it can also be used systemically in severe cases. It is important to note that levorin may have limited effectiveness against certain types of fungi that have developed resistance to polyene antibiotics. Therefore, it is crucial to consult a healthcare professional for proper evaluation and treatment of fungal infections.
Common Misspellings for LEVORIN
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