LEUKOCYTE ADHESION RECEPTORS Meaning and
Definition
-
Leukocyte adhesion receptors are a group of cell surface proteins found on leukocytes, a type of white blood cell, that play a crucial role in the immune response and inflammation processes. These receptors are responsible for the attachment and adhesion of leukocytes to the walls of blood vessels and other tissues, facilitating their migration from the bloodstream to sites of infection or injury.
Leukocyte adhesion receptors are composed of various types of proteins, including selectins, integrins, and immunoglobulin superfamily members. Each type of receptor has its specific ligands and functions. Selectins, for example, are proteins found on the surface of endothelial cells and leukocytes that mediate the initial weak interactions between these cells, allowing the leukocytes to roll along blood vessel walls. Integrins, on the other hand, are proteins that strengthen the adhesion of leukocytes to endothelial cells, allowing them to firmly attach and migrate into tissues.
These adhesion receptors play a crucial role in immune response by enabling leukocytes to navigate through the blood vessels and extravasate into tissues, where they can kill pathogens and initiate an inflammatory response. Dysregulation or dysfunction of these receptors can lead to various diseases, including chronic inflammation, autoimmune disorders, and immunodeficiency syndromes.
The study of leukocyte adhesion receptors is important for understanding the complex cellular mechanisms involved in immune responses and for developing targeted therapies for immune-related diseases.
Common Misspellings for LEUKOCYTE ADHESION RECEPTORS
- keukocyte adhesion receptors
- peukocyte adhesion receptors
- oeukocyte adhesion receptors
- lwukocyte adhesion receptors
- lsukocyte adhesion receptors
- ldukocyte adhesion receptors
- lrukocyte adhesion receptors
- l4ukocyte adhesion receptors
- l3ukocyte adhesion receptors
- leykocyte adhesion receptors
- lehkocyte adhesion receptors
- lejkocyte adhesion receptors
- leikocyte adhesion receptors
- le8kocyte adhesion receptors
- le7kocyte adhesion receptors
- leujocyte adhesion receptors
- leumocyte adhesion receptors
- leulocyte adhesion receptors
- leuoocyte adhesion receptors
- leuiocyte adhesion receptors
