The Leukocyte Adherence Inhibition Test (LAIT) is a diagnostic tool used to measure the functioning of the immune system. The IPA phonetic transcription of this word is /luːkəsaɪt ədˈhiːrəns ɪnˌhɪbɪʃən tɛst/. The pronunciation of "leukocyte" is /ˈluːkəsaɪt/ and pertains to white blood cells. "Adherence" is pronounced /ədˈhiːrəns/ and means sticking or clinging. "Inhibition" is pronounced /ɪnˈhɪbɪʃən/ and refers to the prevention or slowing down of a process. Together, these words form the name of a medical test used to evaluate immune function.
Leukocyte Adherence Inhibition Test is a laboratory technique used to evaluate the body's immune response to foreign substances, such as bacteria or viruses. It measures the ability of white blood cells (leukocytes) to adhere to foreign particles and prevent their invasion into healthy tissues.
In this test, a sample of white blood cells is mixed with a solution containing the foreign substance, also known as an antigen. The leukocytes in the sample interact with the antigen, either by adhering to its surface or engulfing it. By measuring the degree of adherence, scientists can determine the effectiveness of the immune response. If the immune system is functioning properly, the leukocytes will adhere to and inhibit the foreign substance from spreading.
The leukocyte adherence inhibition test is commonly used in the diagnosis and monitoring of certain diseases, such as autoimmune disorders, where the immune system mistakenly attacks healthy tissues. It helps evaluate the immune system's ability to recognize and respond appropriately to foreign substances.
This test is based on the principle that immune cells, particularly lymphocytes, play a crucial role in the body's defense against infections. By measuring the adherence of leukocytes, clinicians can assess the immune system's specific response to certain antigens, providing valuable information for diagnosis, treatment decisions, and monitoring the effectiveness of interventions. Nonetheless, it is essential to interpret these test results in conjunction with a patient's clinical history and other diagnostic tools to make accurate assessments.