KIKUCHI DISEASE Meaning and
Definition
-
Kikuchi Disease, also known as Kikuchi-Fujimoto Disease or histiocytic necrotizing lymphadenitis, is a rare and self-limiting condition characterized by benign enlargement of the lymph nodes along with fever and non-specific constitutional symptoms. It was first described by Dr. Masahiro Kikuchi in 1972 and is most commonly observed in young adults, especially in East Asian populations.
The exact cause of Kikuchi Disease is still unknown, although various theories suggest viral infections like Epstein-Barr virus, human herpesvirus 6, or parvovirus B19 may contribute to its development. The disease primarily affects the lymph nodes, resulting in their enlargement, tenderness, and sometimes the formation of multiple lymphadenopathy clusters. Other symptoms commonly associated with Kikuchi Disease include fever, night sweats, fatigue, rash, and weight loss.
Diagnosis of Kikuchi Disease is often challenging due to its similarities with other lymphoproliferative disorders or infections. Biopsy of an affected lymph node is the key diagnostic procedure, revealing characteristic findings such as necrosis, infiltration of histiocytes, and plasmacytoid monocytes. Laboratory tests may also show elevated levels of inflammatory markers.
Fortunately, Kikuchi Disease is generally self-limiting and resolves within months without specific treatment, although symptomatic management with non-steroidal anti-inflammatory drugs or analgesics may be needed to relieve discomfort. In rare cases, corticosteroids may be prescribed to control severe systemic symptoms. Regular monitoring and follow-up are essential to ensure the resolution of symptoms and rule out the development of any complications.
Overall, Kikuchi Disease is a rare and benign condition characterized by lymph node enlargement and flu-like symptoms, typically resolving without long-term effects on
Common Misspellings for KIKUCHI DISEASE
- jikuchi disease
- mikuchi disease
- likuchi disease
- oikuchi disease
- iikuchi disease
- kukuchi disease
- kjkuchi disease
- kkkuchi disease
- kokuchi disease
- k9kuchi disease
- k8kuchi disease
- kijuchi disease
- kimuchi disease
- kiluchi disease
- kiouchi disease
- kiiuchi disease
- kikychi disease
- kikhchi disease
- kikjchi disease
- kikichi disease
Etymology of KIKUCHI DISEASE
The term "Kikuchi Disease" is named after Masahiro Kikuchi, a Japanese pathologist who first described the condition in 1972. Kikuchi Disease, also known as Kikuchi-Fujimoto Disease or histiocytic necrotizing lymphadenitis, is a rare, self-limiting inflammatory disorder that primarily affects the lymph nodes.
