KETOGLUTARIC ACID Meaning and
Definition
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Ketoglutaric acid is a dicarboxylic acid with the chemical formula C5H6O5. Also known as 2-oxoglutaric acid or alpha-ketoglutaric acid, it belongs to the family of organic compounds called alpha-keto acids. Ketoglutaric acid is an intermediate in the tricarboxylic acid (TCA) cycle, also known as the Krebs cycle or citric acid cycle, which is a vital metabolic pathway in aerobic respiration and energy production in living organisms, including plants, animals, and microorganisms.
In the TCA cycle, ketoglutaric acid is produced through the oxidative decarboxylation of isocitric acid by the enzyme isocitrate dehydrogenase. It then undergoes further transformation into succinyl-CoA, releasing one molecule of carbon dioxide in the process. Ketoglutaric acid plays a crucial role in the TCA cycle as it links other important metabolic pathways, serving as a precursor for the synthesis of various biomolecules such as glutamate, glutamine, and other amino acids.
Besides its role in energy metabolism, ketoglutaric acid has attracted attention in the field of sports nutrition and dietary supplements due to its potential benefits for athletic performance, muscle recovery, and overall health. It is often used as a component in supplements designed to support energy production, enhance exercise endurance, and promote muscle protein synthesis.
Overall, ketoglutaric acid is a fundamental compound in cellular metabolism, essential for the production of energy and the synthesis of essential biomolecules, while also holding potential therapeutic implications in the realm of nutrition and sports performance.
Common Misspellings for KETOGLUTARIC ACID
- jetoglutaric acid
- metoglutaric acid
- letoglutaric acid
- oetoglutaric acid
- ietoglutaric acid
- kwtoglutaric acid
- kstoglutaric acid
- kdtoglutaric acid
- krtoglutaric acid
- k4toglutaric acid
- k3toglutaric acid
- keroglutaric acid
- kefoglutaric acid
- kegoglutaric acid
- keyoglutaric acid
- ke6oglutaric acid
- ke5oglutaric acid
- ketiglutaric acid
- ketkglutaric acid
- ketlglutaric acid
Etymology of KETOGLUTARIC ACID
The word "ketoglutaric acid" has its etymology rooted in both Greek and Latin.
The term "keto" in ketoglutaric comes from the Greek word "ketos", meaning "ketone". In organic chemistry, a ketone is a type of functional group consisting of a carbonyl group (C=O) bonded to two carbon atoms.
The word "glutaric" comes from the Latin "glutārum", which means "of wheat flour". This is derived from "glūten", referring to glue or gluey substance, as wheat flour, when moistened, forms a sticky mass. The use of "glutaric" in the compound name likely refers to the four-carbon chain structure of the acid.
Lastly, the term "acid" is a general term derived from the Latin "acidus", which means "sour".
