JURKAT CELL Meaning and
Definition
-
Jurkat cells are a type of immortalized T-cell line widely used in biological and immunological research as an in vitro model. These cells were established from the peripheral blood of a T-cell lymphoma patient, allowing researchers to explore various aspects of T-cell function, signaling, and response to external factors.
Jurkat cells are characterized by their continuous proliferation and ability to maintain T-cell-like properties, making them a suitable model to study T-cell biology and behavior. These cells represent a widely used human T-cell model for investigating mechanisms related to cell activation, differentiation, apoptosis, and immune response.
The main advantage of Jurkat cells is their well-characterized nature, providing consistency and reproducibility across different experiments. Moreover, Jurkat cells possess similar functional properties to primary human T-cells, offering researchers the opportunity to investigate T-cell-related processes in a more controlled and homogenous environment.
Researchers often utilize Jurkat cells to study various diseases, including cancer, autoimmune disorders, and viral infections, as well as T-cell-based therapies. By using Jurkat cells, scientists can investigate the impact of specific molecules, drugs, or genetic modifications on T-cell function and behavior.
In conclusion, Jurkat cells are a valuable tool in immunological and biological research, serving as a model system to understand T-cell biology, immune responses, and various diseases. Their well-characterized nature enables controlled experimentation, making Jurkat cells a fundamental resource for advancing scientific knowledge and potential therapeutic developments.
Common Misspellings for JURKAT CELL
- hurkat cell
- nurkat cell
- murkat cell
- kurkat cell
- iurkat cell
- uurkat cell
- jyrkat cell
- jhrkat cell
- jjrkat cell
- jirkat cell
- j8rkat cell
- j7rkat cell
- juekat cell
- judkat cell
- jufkat cell
- jutkat cell
- ju5kat cell
- ju4kat cell
- jurjat cell
- jurmat cell
Etymology of JURKAT CELL
The term "Jurkat cell" is named after its original source, the patient from whom it was derived, and the laboratory that used it for research.
The Jurkat cell line was established in the 1970s by German virologist and immunologist Hans Jürgen "Jurgen" Jondal and his colleagues. They obtained a sample of malignant T-lymphocytes (cancerous white blood cells) from the blood of a fourteen-year-old boy diagnosed with acute lymphoblastic leukemia (ALL) named Peter Jurkat.
The cells were cultured and immortalized, resulting in the establishment of a continuous cell line known as the "Jurkat cell". These cells have since become a widely used model in immunology and cancer research, particularly in the study of T-cell biology and various diseases associated with T-cells.
