ISOCHROMOSOME Meaning and
Definition
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Isochromosome is a genetic abnormality that occurs when a chromosome duplicates or replicates incorrectly. In an isochromosome, one of the arms of the chromosome gets duplicated, while the other arm is lost. As a result, the two arms of the chromosome are identical or nearly identical, giving the chromosome a mirrored or symmetrical appearance.
Isochromosomes are typically formed due to errors during cell division, specifically in the formation of sister chromatids. The structure and stability of isochromosomes can vary depending on the affected chromosome and the specific location where the abnormality occurs.
The presence of isochromosomes can lead to various genetic disorders and health conditions. It can result in rearrangements of genetic material, affecting the function of specific genes and disrupting normal cellular processes. Some common disorders associated with isochromosomes include Turner syndrome, Pallister-Killian syndrome, and several types of cancer.
Detection of isochromosomes can be done through various laboratory techniques, such as karyotyping, fluorescence in situ hybridization (FISH), or molecular genetic testing. These methods help in identifying the presence of the abnormal chromosome structure and determining the specific chromosomal region affected.
Understanding isochromosomes and their impact on human health is crucial as it aids in diagnosing and managing related genetic disorders. While treatment options may vary depending on the specific condition associated with the isochromosome, genetic counseling and supportive therapies can play a vital role in improving the quality of life for affected individuals.
Common Misspellings for ISOCHROMOSOME
- usochromosome
- jsochromosome
- ksochromosome
- osochromosome
- 9sochromosome
- 8sochromosome
- iaochromosome
- izochromosome
- ixochromosome
- idochromosome
- ieochromosome
- iwochromosome
- isichromosome
- iskchromosome
- islchromosome
- ispchromosome
- is0chromosome
- is9chromosome
- isoxhromosome
- isovhromosome
Etymology of ISOCHROMOSOME
The word "isochromosome" is derived from two root words: "iso" and "chromosome".
1. "Iso" comes from the Greek word "ísos" (ἴσος), which means "equal" or "same". This root is commonly used in scientific terminology to denote something that is equal or uniform.
2. "Chromosome" comes from two Greek words: "chrōma" (χρῶμα), meaning "color", and "sōma" (σῶμα), meaning "body". The term was coined by the German anatomist Wilhelm von Waldeyer-Hartz in 1888 to describe the colored thread-like structures observed in the nucleus of cells during cell division.
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