INTRINSIC PATHWAY Meaning and
Definition
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The intrinsic pathway refers to a specific cascade of biochemical reactions that occur within the body in response to cellular damage or injury. It is a critical component of the blood clotting process, also known as coagulation, which helps to prevent excessive bleeding. The intrinsic pathway is activated by internal factors present in the bloodstream, hence the term "intrinsic."
When tissue damage occurs, certain substances, such as collagen, are exposed to the blood. This exposure triggers a series of reactions in which proteins in the plasma, known as clotting factors, interact with each other in a sequential manner. These interactions form a complex network that ultimately leads to the formation of a stable blood clot, sealing the damaged area.
The intrinsic pathway involves several key steps. Firstly, the activation of factor XII initiates a cascade of events, resulting in the sequential activation of other clotting factors, including factor XI, factor IX, and factor VIII. These factors promote the production of thrombin, an enzyme responsible for converting fibrinogen into insoluble fibrin strands, which form the basis of a blood clot.
The intrinsic pathway plays a crucial role in the body's natural defense mechanism against bleeding. Disorders or abnormalities in the activation or regulation of this pathway can lead to various medical conditions, such as hemophilia, which is characterized by abnormal clotting and excessive bleeding. Understanding the intrinsic pathway is essential for clinical purposes, such as diagnosing and managing coagulation disorders or guiding interventions to prevent or manage excessive bleeding.
Common Misspellings for INTRINSIC PATHWAY
- untrinsic pathway
- jntrinsic pathway
- kntrinsic pathway
- ontrinsic pathway
- 9ntrinsic pathway
- 8ntrinsic pathway
- ibtrinsic pathway
- imtrinsic pathway
- ijtrinsic pathway
- ihtrinsic pathway
- inrrinsic pathway
- infrinsic pathway
- ingrinsic pathway
- inyrinsic pathway
- in6rinsic pathway
- in5rinsic pathway
- inteinsic pathway
- intdinsic pathway
- intfinsic pathway
- inttinsic pathway
Etymology of INTRINSIC PATHWAY
The term "intrinsic pathway" in the context of biology and biochemistry refers to a series of events or processes that occur within an organism itself, without being influenced by external factors or stimuli. The etymology of the word "intrinsic" can be traced back to the Latin word "intrinsecus", meaning "on the inside" or "within".
The word "pathway" comes from the Middle English word "pathewai", which was formed by combining the words "path" (from the Old English word "paþ", meaning "a way or track") and "way" (from the Old English word "weg", meaning "a route or road").
