INTRINSIC FACTOR Meaning and
Definition
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Intrinsic factor is a protein produced by the parietal cells of the stomach that is essential for the absorption of vitamin B12 in the small intestine. It is characterized by its role in binding to vitamin B12, protecting it from degradation by stomach acid, and facilitating its transport to the terminal ileum, which is the part of the small intestine where B12 absorption occurs.
The production and secretion of intrinsic factor is regulated by the presence of gastrin, a hormone released by the stomach in response to the presence of food. Intrinsic factor binds to vitamin B12 in the stomach, forming a complex that is resistant to degradation by gastric acid. Once this complex reaches the small intestine, it is recognized and bound by specific receptors on the surface of cells in the terminal ileum. This allows for the efficient absorption of vitamin B12 into the bloodstream.
Individuals who lack intrinsic factor, either due to genetic factors or certain medical conditions, may develop a condition known as pernicious anemia. In pernicious anemia, the absence of intrinsic factor results in an inability to absorb adequate amounts of vitamin B12, leading to a deficiency that can cause symptoms such as fatigue, weakness, and neurological problems.
Overall, intrinsic factor plays a crucial role in the absorption of vitamin B12, thereby contributing to various essential functions in the body, including the production of red blood cells and the maintenance of a healthy nervous system.
Common Misspellings for INTRINSIC FACTOR
- untrinsic factor
- jntrinsic factor
- kntrinsic factor
- ontrinsic factor
- 9ntrinsic factor
- 8ntrinsic factor
- ibtrinsic factor
- imtrinsic factor
- ijtrinsic factor
- ihtrinsic factor
- inrrinsic factor
- infrinsic factor
- ingrinsic factor
- inyrinsic factor
- in6rinsic factor
- in5rinsic factor
- inteinsic factor
- intdinsic factor
- intfinsic factor
Etymology of INTRINSIC FACTOR
The word "intrinsic" originates from the Latin word "intrinsecus", which means "interior" or "inner". It was formed by combining the prefix "in-" meaning "within, inside" and "trinsecus", meaning "outer, external".
The term "factor" has its roots in the Latin word "facere", meaning "to make" or "to do". In medical terminology, "factor" often refers to a substance or agent that contributes to a specific process or function within the body.
Therefore, when combined, "intrinsic factor" can be understood as a substance or agent present within the body that contributes to a particular function or process. In medicine, the term specifically refers to a glycoprotein essential for the absorption of vitamin B12 in the small intestine.
Similar spelling words for INTRINSIC FACTOR
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