INDOXYL SULFATE Meaning and
Definition
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Indoxyl sulfate is a chemical compound that belongs to the class of organic compounds known as substituted phenols. It is derived from the metabolic breakdown of dietary tryptophan, an essential amino acid found in various food sources. Indoxyl sulfate is mainly produced in the liver, where it is converted from indole, a byproduct of tryptophan metabolism. It is then transported via the bloodstream and excreted by the kidneys into the urine.
Indoxyl sulfate has been extensively studied for its potential role as a biomarker in various medical conditions, primarily chronic kidney disease. High levels of indoxyl sulfate have been associated with impaired kidney function, as it is predominantly eliminated through renal excretion. Furthermore, indoxyl sulfate has been implicated in the development of renal fibrosis, oxidative stress, and inflammation, which can contribute to the progression of kidney disease.
In addition to its role as a biomarker, indoxyl sulfate has also been linked to the pathogenesis of atherosclerosis and cardiovascular disease. It exerts toxic effects on endothelial cells, promotes the formation of reactive oxygen species, and initiates inflammatory responses, all of which are known factors in the development of atherosclerotic plaques.
Overall, indoxyl sulfate plays a significant role in several pathological processes, particularly in kidney disease and cardiovascular complications. Further understanding of its mechanisms of action and potential therapeutic interventions may offer new insights into the prevention and treatment of these conditions.
Common Misspellings for INDOXYL SULFATE
- undoxyl sulfate
- jndoxyl sulfate
- kndoxyl sulfate
- ondoxyl sulfate
- 9ndoxyl sulfate
- 8ndoxyl sulfate
- ibdoxyl sulfate
- imdoxyl sulfate
- ijdoxyl sulfate
- ihdoxyl sulfate
- insoxyl sulfate
- inxoxyl sulfate
- incoxyl sulfate
- infoxyl sulfate
- inroxyl sulfate
- ineoxyl sulfate
- indixyl sulfate
- indkxyl sulfate
- indlxyl sulfate
- indpxyl sulfate
Etymology of INDOXYL SULFATE
The word "Indoxyl Sulfate" is a chemical compound name consisting of two parts: "indoxyl" and "sulfate".
- "Indoxyl" is derived from the term "indigo", which refers to a blue dye commonly used in industries such as textiles and printing. The term "indigo" has its roots in the Greek word "indikon", which came from the Persian word "indigon", meaning "Indian dye".
- "Sulfate" is derived from the Latin word "sulfur", which means "sulfur" or "brimstone". "Sulfur" itself has ancient roots and is believed to have originated from the Sanskrit word "sulvere", meaning "to burn".
Combining these two parts, "Indoxyl Sulfate" refers to a sulfate compound containing the molecular structure of "indoxyl".
