How Do You Spell IMMUNOLOGIC CYTOTOXICITY TESTS?

Pronunciation: [ɪmjˌuːnəlˈɒd͡ʒɪk sˌa͡ɪtətəksˈɪsɪti tˈɛsts] (IPA)

Immunologic Cytotoxicity Tests (ɪˌmjʊnəˈlɑdʒɪk saɪtəˌtɑksɪˈkɑtəti tɛsts) are a type of diagnostic test used to measure the ability of certain immune system cells to cause death to target cells. The word "immunologic" refers to the study of the immune system, while "cytotoxicity" is the ability of immune cells to kill other cells. The spelling of this word is based on the phonetic transcription of each syllable, with emphasis placed on the syllables "im-mu-no" and "cy-to-tox-i-ci-ty" to demonstrate their importance in the word.

Meaning and Definition
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IMMUNOLOGIC CYTOTOXICITY TESTS Meaning and Definition

  1. Immunologic cytotoxicity tests refer to a set of laboratory-based assays used to evaluate the ability of certain immune cells or molecules to destroy target cells. These tests play a crucial role in identifying and characterizing cellular immune responses involved in various diseases, including autoimmune disorders, allergies, and immune system deficiencies.

    In these tests, target cells, typically cancer or infected cells, are labeled with a dye or radioactive material to facilitate their identification. Immune cells, such as natural killer (NK) cells or cytotoxic T lymphocytes (CTLs), are then added to the mixture. If the immune cells recognize the target cells as foreign or abnormal, they initiate a response by releasing cytotoxic substances that aim to destroy them.

    There are different types of immunologic cytotoxicity tests, depending on the specific parameters being evaluated. Examples include antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) assays. ADCC tests assess the ability of certain antibodies to bind to target cells and activate immune cells to destroy them. CDC tests, on the other hand, focus on the activation of the complement system, a group of proteins that can directly lead to the destruction of target cells.

    The results of immunologic cytotoxicity tests are typically quantified by measuring the percentage of target cell destruction or the effector-to-target ratio. These tests provide valuable insights into the immune system's ability to eliminate abnormal cells and play a crucial role in diagnosing and monitoring disease progression, as well as evaluating the effectiveness of immunotherapies and vaccines.

Common Misspellings for IMMUNOLOGIC CYTOTOXICITY TESTS

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