IMIDAZOLE Meaning and
Definition
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Imidazole is a heterocyclic organic compound that consists of a five-membered ring comprising three carbon atoms, two nitrogen atoms, and two double bonds. It has the molecular formula C3H4N2. Imidazole is a colorless or pale yellow solid with a strong and characteristic odor. It is soluble in water, alcohol, and other organic solvents.
In terms of its chemical properties, imidazole is considered a weak base as it can accept a proton. It is also weakly acidic due to the presence of two nitrogen atoms that can donate electrons. The imidazole ring is relatively stable, and its structure allows for various interactions like hydrogen bonding and pi-stacking. These properties make imidazole a key component in a wide range of biochemical processes and a building block in the synthesis of many pharmaceutical compounds.
Imidazole plays a crucial role in biological systems, particularly as a component of histidine, an essential amino acid found in proteins. It is involved in various enzymatic reactions, acting as a catalyst and helping to stabilize protein structures. Imidazole derivatives are also used as drugs to treat various medical conditions, including fungal and parasitic infections, as well as certain types of cancer.
Additionally, imidazole has applications in organic synthesis, particularly in the formation of heterocyclic compounds. It can be employed as a versatile ligand in coordination chemistry. Imidazole derivatives are commonly used in industries such as agrochemicals, dyes, and polymers. Overall, imidazole serves as a vital molecular scaffold with diverse biological and chemical applications.
Common Misspellings for IMIDAZOLE
- umidazole
- jmidazole
- kmidazole
- omidazole
- 9midazole
- 8midazole
- inidazole
- ikidazole
- ijidazole
- imudazole
- imjdazole
- imkdazole
- imodazole
- im9dazole
- im8dazole
- imisazole
- imixazole
- imicazole
- imifazole
Etymology of IMIDAZOLE
The word "imidazole" was derived from the combination of two roots: "imide" and "azole".
The root "imide" is derived from the word "imido", which refers to a chemical compound formed by replacing the oxygen in a carboxylic acid group with a nitrogen atom. The term "imide" was first used by French chemist Antoine Lavoisier in the late 18th century.
The second part, "azole", is derived from the Greek word "azolē" (ἀζολή), which means "nitrogen". This term was introduced by German chemist Emil Fischer in 1887 for a class of organic compounds containing at least one nitrogen atom in a five-membered ring. "Azole" is also the general class name for a group of heterocyclic compounds that share a similar structure.
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