HYPERGLOBULINEMIC PURPURA Meaning and
Definition
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Hyperglobulinemic purpura, also known as Waldenström's purpura, is a rare autoimmune disorder characterized by the deposition of immune complexes in small blood vessels. This condition is predominantly observed in elderly individuals and is more common in women than in men. The term "hyperglobulinemic" refers to an increased level of globulins, a type of protein, in the blood.
The hallmark symptom of hyperglobulinemic purpura is the development of purpura, which are purple or red-colored spots or patches on the skin caused by bleeding underneath. Purpura usually appear on the lower limbs, but can also affect other areas of the body. Other symptoms may include joint pain, fatigue, and general weakness.
The exact cause of hyperglobulinemic purpura is not well understood. It is thought to develop as a result of an abnormal immune response in which the body's immune system produces excessive amounts of immunoglobulins, specifically IgM antibodies. These antibodies form immune complexes that accumulate in the small blood vessels, leading to inflammation and damage.
Diagnosis of hyperglobulinemic purpura may involve a thorough physical examination, blood tests to check for increased levels of globulins and other antibodies, and a biopsy of the affected skin to confirm the presence of immune complexes.
Treatment for hyperglobulinemic purpura aims to manage the symptoms and reduce inflammation. This may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs) to relieve joint pain and swelling, as well as corticosteroids or immunosuppressive medications to suppress the abnormal immune response. In severe cases, plasmapheresis, a procedure that removes antibodies from the blood, may be considered. Long-term follow-up and regular monitoring are
Common Misspellings for HYPERGLOBULINEMIC PURPURA
- gyperglobulinemic purpura
- byperglobulinemic purpura
- nyperglobulinemic purpura
- jyperglobulinemic purpura
- uyperglobulinemic purpura
- yyperglobulinemic purpura
- htperglobulinemic purpura
- hgperglobulinemic purpura
- hhperglobulinemic purpura
- huperglobulinemic purpura
- h7perglobulinemic purpura
- h6perglobulinemic purpura
- hyoerglobulinemic purpura
- hylerglobulinemic purpura
- hy-erglobulinemic purpura
- hy0erglobulinemic purpura
- hypwrglobulinemic purpura
- hypsrglobulinemic purpura
- hypdrglobulinemic purpura
- hyprrglobulinemic purpura
Etymology of HYPERGLOBULINEMIC PURPURA
The word "Hyperglobulinemic Purpura" can be broken down into its components to understand its etymology:
1. Hyper-: a prefix derived from Greek meaning "excessive" or "above normal".
2. Globulinemic: related to the term "globulinemia". "Globulin" is derived from the Latin word "globus" meaning "small sphere" and the suffix "-in" denotes a substance. "Emia" is derived from the Greek word "aima" meaning "blood" and is used as a suffix in medical terminology to refer to a condition related to the blood.
3. Purpura: derived from the Latin word "purpura" meaning "purple". This term is used in medical terminology to refer to an abnormal condition characterized by purple or red discolorations on the skin caused by bleeding under the skin.
