HYDROXYPROLINE Meaning and
Definition
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Hydroxyproline is a non-proteinogenic amino acid derived from the amino acid proline. It is an essential component of collagen, a fibrous structural protein found in connective tissues such as skin, bones, tendons, and cartilage.
The chemical structure of hydroxyproline contains an additional hydroxyl (OH) group attached to the carbon atom of proline. This unique functional group gives hydroxyproline distinctive properties, making it crucial for collagen stability and structure.
Hydroxyproline plays a fundamental role in collagen formation and maturation. During the synthesis of collagen, specific enzymes hydroxylate proline residues, converting them into hydroxyproline. These hydroxylated proline residues are essential for the stability and stability of collagen helices, as they form stable hydrogen bonds within the collagen triple helix, reinforcing its structure.
In addition to its structural role, hydroxyproline is also integral to collagen's functional properties. Collagen containing hydroxyproline is resistant to denaturation by heat or enzymes, making it highly stable and durable. Hydroxyproline also plays a significant role in collagen fibrillogenesis, the process by which collagen fibrils form and organize.
Because hydroxyproline is unique to collagen, it serves as an important biomarker for collagen synthesis and turnover rates. Quantifying hydroxyproline levels in biological samples or tissues can provide valuable insights into collagen metabolism and overall connective tissue health.
Common Misspellings for HYDROXYPROLINE
- gydroxyproline
- bydroxyproline
- nydroxyproline
- jydroxyproline
- uydroxyproline
- yydroxyproline
- htdroxyproline
- hgdroxyproline
- hhdroxyproline
- hudroxyproline
- h7droxyproline
- h6droxyproline
- hysroxyproline
- hyxroxyproline
- hycroxyproline
- hyfroxyproline
- hyrroxyproline
- hyeroxyproline
- hydeoxyproline
Etymology of HYDROXYPROLINE
The word "hydroxyproline" is derived from two components: "hydroxy" and "proline".
The term "hydroxy" comes from the Greek word "hydor", meaning "water", and the suffix "-oxy", which indicates the presence of oxygen. Therefore, "hydroxy" refers to a molecule or functional group that contains a hydroxyl group (-OH), which is composed of oxygen and hydrogen atoms.
"Proline" originates from the Greek word "pro", meaning "before" or "in front of", and the word "liqueur", which refers to a liquid. "Proline" is an amino acid, one of the building blocks of proteins, which was first isolated from hydrolysates of gelatin, a protein obtained from animal connective tissue. It was named "proline" to indicate it is a derivative or precursor of a primary substance.
Similar spelling words for HYDROXYPROLINE
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