Hydrazone is a chemical compound that contains a nitrogen molecule and a carbonyl group. The spelling of hydrazone accurately reflects its pronunciation using the International Phonetic Alphabet (IPA). The "h" is silent, and the "y" is pronounced as /aɪ/. The "d" is pronounced as /d/ and the "r" is pronounced as /r/. The "a" is pronounced as /ə/, and the "z" is pronounced as /z/. Finally, the "o" is pronounced as /əʊ/, and the "ne" is pronounced as /n/. Thus, hydrazone's spelling represents the sounds that create this compound's name.
Hydrazone is a chemical compound characterized by the presence of a carbon-nitrogen double bond (C=N) and an additional nitrogen atom bonded to a hydrogen atom (–NH–NH2). It is derived from the condensation reaction between hydrazine or one of its derivatives and a carbonyl compound, typically an aldehyde or a ketone. Hydrazone compounds possess a general formula of R1R2C=NNH–NH2, where R1 and R2 represent different organic substituents attached to the carbon and nitrogen atoms, respectively.
Hydrazones are commonly used in organic synthesis as intermediates for various applications. They exhibit versatile reactivity due to the presence of the carbon-nitrogen double bond, allowing for further manipulations and functionalizations. Hydrazone compounds can undergo reactions such as oxidation, reduction, and acylation to yield a wide range of products with diverse functionality. Moreover, their stability and ease of synthesis make hydrazones valuable building blocks for the construction of more complex organic molecules.
The development and application of hydrazones extend beyond organic chemistry. They find utility in pharmaceutical research as potential drug candidates due to their diverse biological activities. Additionally, hydrazones possess fluorescent properties, making them useful in analytical chemistry, particularly in fluorescent labeling and detection techniques.
In summary, hydrazone is a class of organic compounds characterized by the presence of a carbon-nitrogen double bond (C=N) and an additional nitrogen atom bonded to a hydrogen atom (–NH–NH2). They are versatile intermediates commonly used in organic synthesis and possess various properties that make them valuable in fields such as pharmaceutical research and analytical chemistry.
A substance derived from aldehydes and ketones by reaction with phenylhydrazine.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "hydrazone" is derived from the Greek words "hydor", meaning water, and "zone", meaning band or belt. This term was coined by the German chemist Emil Fischer in the late 19th century to describe a class of organic compounds containing the characteristic group NHN=, which resembles a belt around a water molecule.