HUMAN UBIQUITIN Meaning and
Definition
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Human Ubiquitin
Human ubiquitin is a small protein molecule that is extremely prevalent within the cells of all eukaryotic organisms, including humans. It plays a crucial role in a process known as ubiquitination, which is a fundamental cellular mechanism for targeted protein degradation, cell signaling, and regulation of various physiological processes.
Ubiquitin consists of 76 amino acids and is highly conserved across different species, indicating its fundamental importance in cellular physiology. It is characterized by its ability to attach to target proteins through a covalent binding process known as ubiquitination. This process involves a series of enzymatic reactions, starting with the activation of ubiquitin by an enzyme called E1 activating enzyme. Subsequently, the activated ubiquitin is transferred to an intermediate enzyme known as E2 conjugating enzyme, which eventually binds to the target protein through a final enzyme called E3 ligase. This process can occur multiple times, leading to the attachment of several ubiquitin molecules to a single target protein, forming a ubiquitin chain.
Once a protein is ubiquitinated, it is recognized by the proteasome, a cellular machinery responsible for protein degradation. The ubiquitin chain acts as a molecular tag, marking the protein for degradation by the proteasome, thereby maintaining cellular homeostasis and regulating protein turnover. Moreover, ubiquitin chains can also serve as docking sites for various proteins involved in signal transduction pathways, influencing protein-protein interactions and cellular processes like DNA repair, cell cycle progression, and immune response.
In summary, human ubiquitin is an essential protein involved in ubiquitination, a process that regulates protein degradation, signaling, and various physiological functions in the cell.
Common Misspellings for HUMAN UBIQUITIN
- guman ubiquitin
- buman ubiquitin
- numan ubiquitin
- juman ubiquitin
- uuman ubiquitin
- yuman ubiquitin
- hyman ubiquitin
- hhman ubiquitin
- hjman ubiquitin
- himan ubiquitin
- h8man ubiquitin
- h7man ubiquitin
- hunan ubiquitin
- hukan ubiquitin
- hujan ubiquitin
- humzn ubiquitin
- humsn ubiquitin
- humwn ubiquitin
- humqn ubiquitin
- humab ubiquitin
Etymology of HUMAN UBIQUITIN
The word "ubiquitin" is derived from the Latin word "ubique", which means "everywhere" or "ubiquitous". The term "ubiquitin" was specifically coined by combining "ubi-" (from Latin "ubique") with "tin", signifying a protein.
Regarding "human ubiquitin", the adjective "human" denotes the species to which the ubiquitin protein belongs. It signifies that the ubiquitin being referred to is specifically found in humans, distinguishing it from ubiquitin found in other organisms.
