The HGNC, also known as the HUGO Gene Nomenclature Committee, is an international organization responsible for assigning unique names and symbols to human genes. The HGNC acts as the official authority in gene nomenclature, ensuring standardized and consistent naming conventions for the scientific community and facilitating efficient communication and comprehension of genetic research.
Human genes are identified and named based on their discovered functions, genetic sequences, or association with specific diseases or phenotypes. The HGNC manages a comprehensive database containing information on all previously named human genes, along with their approved symbols, aliases, and associated data.
The primary purpose of the HGNC is to establish a uniform system for gene names to prevent confusion and ambiguity in scientific literature, research studies, and clinical applications. By providing a centralized resource for gene nomenclature, the HGNC aids researchers, clinicians, and geneticists in accurately identifying and studying specific genes and their variants. This standardization allows for easier collaboration, comparison of research findings, and understanding of genetic information across various scientific disciplines and institutions.
Moreover, the HGNC continually updates and revises gene names and symbols to reflect advancements in scientific knowledge and understandings. This ensures that gene nomenclature remains up-to-date, accurate, and relevant, supporting ongoing research efforts and avoiding confusion caused by outdated or duplicate gene names.
