HEREDITARY ELLIPTOCYTOSES Meaning and
Definition
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Hereditary elliptocytoses refer to a group of genetic disorders characterized by abnormal elliptical-shaped red blood cells (elliptocytes) in the bloodstream. This condition is inherited in an autosomal dominant pattern, meaning that an affected individual has a 50% chance of passing the mutation to each of their children.
The elliptocytosis disorders are primarily caused by mutations in genes responsible for encoding proteins involved in the structure and stability of red blood cells. These mutations typically affect the organization and function of the cytoskeleton of red blood cells, leading to their abnormal shape and decreased flexibility. The cytoskeleton is essential for maintaining the integrity and stability of these cells, which is crucial for their passage through narrow blood vessels and capillaries.
Individuals with hereditary elliptocytoses may exhibit a wide range of clinical symptoms, including varying degrees of chronic anemia, jaundice, and splenomegaly. Some affected individuals may also experience intermittent episodes of jaundice and gallstones due to the increased breakdown of red blood cells and bilirubin accumulation.
Diagnosis of hereditary elliptocytoses is generally based on blood tests to analyze the shape, size, and stability of red blood cells. Additionally, genetic testing may be done to identify specific mutations associated with this condition.
Management of hereditary elliptocytoses is typically focused on alleviating symptoms and preventing complications. Treatment may involve blood transfusions, folic acid supplementation to support red blood cell production, and splenectomy (surgical removal of the spleen) in severe cases. Regular monitoring and genetic counseling are essential aspects of patient care to provide appropriate guidance and support.
Common Misspellings for HEREDITARY ELLIPTOCYTOSES
- gereditary elliptocytoses
- bereditary elliptocytoses
- nereditary elliptocytoses
- jereditary elliptocytoses
- uereditary elliptocytoses
- yereditary elliptocytoses
- hwreditary elliptocytoses
- hsreditary elliptocytoses
- hdreditary elliptocytoses
- hrreditary elliptocytoses
- h4reditary elliptocytoses
- h3reditary elliptocytoses
- heeeditary elliptocytoses
- hededitary elliptocytoses
- hefeditary elliptocytoses
- heteditary elliptocytoses
- he5editary elliptocytoses
- he4editary elliptocytoses
- herwditary elliptocytoses
- hersditary elliptocytoses
Etymology of HEREDITARY ELLIPTOCYTOSES
The etymology of the term "Hereditary Elliptocytoses" can be broken down as follows:
1. Hereditary: This term comes from the Latin word "hereditarius", which means "inherited". It refers to a condition or trait that is passed down from generation to generation through genetic transmission.
2. Elliptocytoses: This term is derived from two components: "ellipto-" and "-cytoses".
- Ellipto-: This prefix is derived from the Greek word "elleiptos", meaning "elliptical" or "oval". It indicates the characteristic shape of red blood cells affected by this condition, which are elliptical instead of the typical disc shape.
- -cytoses: This suffix is derived from the Greek word "kutos", which means "cell". It is used in medical terminology to denote an increase or abnormal proliferation of cells.
