GUANETHIDINE MONOSULFATE Meaning and
Definition
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Guanethidine monosulfate is a medication that belongs to the class of sympatholytic drugs. It is an adrenergic neuronal blocker used primarily in the treatment of hypertension (high blood pressure). When administered orally or intravenously, guanethidine monosulfate selectively blocks the release of neurotransmitters called norepinephrine (noradrenaline) from the synaptic vesicles, thereby inhibiting the transmission of sympathetic nerve impulses.
By blocking the release of norepinephrine, guanethidine monosulfate interferes with the normal functioning of the sympathetic nervous system, which controls various involuntary bodily functions, including blood pressure regulation. This blockade results in a decrease in peripheral vascular resistance and heart rate, leading to the lowering of blood pressure.
Guanethidine monosulfate is usually prescribed as an adjunctive treatment in cases where other antihypertensive drugs have failed to adequately control blood pressure. It may be used alone or in combination with other medications. The dosage and duration of treatment may vary depending on the patient's condition and response to therapy.
It is important to note that guanethidine monosulfate can cause several side effects, including postural hypotension (low blood pressure when changing positions), dizziness, dry mouth, constipation, and sexual dysfunction. Therefore, it is crucial for individuals taking this medication to consult with their healthcare provider regularly to monitor blood pressure levels and assess the overall response to treatment.
Common Misspellings for GUANETHIDINE MONOSULFATE
- fuanethidine monosulfate
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Etymology of GUANETHIDINE MONOSULFATE
The word "Guanethidine" is derived from "guanidine", which refers to a chemical compound containing the guanidine functional group. Guanidine itself is derived from the French term "guanine", which originally denoted a crystalline substance found in guano (bird droppings). The term "monosulfate" is a combination of "mono-" meaning "one" and "sulfate", referring to a compound containing the sulfate ion (SO4^2-). Therefore, "Guanethidine Monosulfate" represents the combination of guanethidine with one sulfate molecule.
