GRADE II ASTROCYTOMAS Meaning and
Definition
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Grade II astrocytomas are a type of brain tumor that belong to the category of astrocytic tumors. Astrocytomas are tumors that arise from the star-shaped cells called astrocytes, which are a type of glial cell found in the brain and spinal cord.
Grade II astrocytomas are considered low-grade tumors, indicating a slower growth rate compared to higher grade tumors. These tumors are characterized by diffuse infiltration into the surrounding brain tissue, making complete surgical removal challenging. The cells of Grade II astrocytomas generally appear normal under a microscope, exhibiting minimal cytological atypia, or abnormalities.
Although these tumors are classified as slow-growing, over time they have the potential to progress into higher grades, such as grade III or grade IV astrocytomas, which have a more aggressive growth pattern. Common symptoms associated with Grade II astrocytomas may include persistent and worsening headaches, seizures, changes in personality or behavior, difficulty with balance or coordination, and focal neurological deficits.
Grade II astrocytomas are typically managed through a combination of surgical resection, radiation therapy, and chemotherapy. Concerns regarding the potential transformation of these tumors into higher grades drives the need for regular monitoring and follow-up through imaging techniques such as magnetic resonance imaging (MRI) scans. Prognosis for Grade II astrocytomas varies, with some patients experiencing long-term survival and others progressing to a higher grade or experiencing tumor recurrence.
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