GLYCOPROTEOME Meaning and
Definition
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The glycoproteome is a term used in the field of molecular biology to describe the entire complement of glycoproteins found within a particular cell, tissue, organism, or biological system. It refers to the subset of proteins that have undergone post-translational modification called glycosylation, where sugar molecules are enzymatically attached to specific amino acids present in the protein sequence.
Glycoproteins play crucial roles in various biological processes, such as cellular recognition, immune response, cell-cell communication, and protein stability. The glycoproteome encompasses the diverse range of these modified proteins, including integral membrane glycoproteins, secreted glycoproteins, and glycoproteins present within cellular compartments like the endoplasmic reticulum and Golgi apparatus.
The study of the glycoproteome involves a combination of proteomic techniques, such as mass spectrometry, and specific strategies to enrich and analyze glycosylated proteins. By characterizing and cataloging the glycoproteome, researchers aim to uncover the roles and functions of specific glycoproteins, understand their involvement in disease processes, identify potential biomarkers, and discover new therapeutic targets.
The glycoproteome is a dynamic entity that can vary between different cell types, tissues, developmental stages, and physiological conditions. Therefore, understanding the glycoproteome of specific biological systems is crucial for unraveling the complex networks of cellular activities and intercellular communications, ultimately leading to advancements in areas such as diagnostics, therapeutics, and personalized medicine.
Common Misspellings for GLYCOPROTEOME
- flycoproteome
- vlycoproteome
- blycoproteome
- hlycoproteome
- ylycoproteome
- tlycoproteome
- gkycoproteome
- gpycoproteome
- goycoproteome
- gltcoproteome
- glgcoproteome
- glhcoproteome
- glucoproteome
- gl7coproteome
- gl6coproteome
- glyxoproteome
- glyvoproteome
- glyfoproteome
- glydoproteome
- glyciproteome
Etymology of GLYCOPROTEOME
The word "glycoproteome" is derived from two main components: "glyco-" and "proteome".
1. "Glyco-" is derived from the Greek word "glykys", meaning "sweet" or "sugar". It is usually used in the context of carbohydrates or sugars.
2. "Proteome" is a combination of "protein" and "genome". "Protein" originates from the Greek word "proteios", meaning "primary" or "first rank". "Genome", on the other hand, refers to the complete set of genes or genetic material of an organism.
When combined, "glycoproteome" refers to the complete set of glycoproteins in a particular cell, tissue, or organism. Glycoproteins are proteins that have attached carbohydrate molecules. The word indicates a focus on the study and analysis of these specific protein-carbohydrate complexes.
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