How Do You Spell GLYCOPROTEIN SIALYLTRANSFERASES?

Pronunciation: [ɡlˈa͡ɪkəpɹˌə͡ʊtiːn sˈa͡ɪəlˌɪltɹɐnsfˌɜːɹe͡ɪzɪz] (IPA)

The word "Glycoprotein Sialyltransferases" is quite a mouthful, but its spelling is easily explained with phonetics. "Glyco" is pronounced as "glai-koh" (IPA: /ɡlaɪkoʊ/), "pro" as "prō" (IPA: /proʊ/), and "tein" as "tēn" (IPA: /teɪn/). "Sialyl" is pronounced as "sai-uh-lil" (IPA: /saɪəlɪl/), and "transferases" as "trans-fur-ay-siz" (IPA: /trænsˈfɜreɪsɪz/). Altogether, the word refers to a class of enzymes involved in the modification of glycoproteins, and its spelling can be deciphered with the

GLYCOPROTEIN SIALYLTRANSFERASES Meaning and Definition

1. Glycoprotein sialyltransferases are enzymes that play a crucial role in the post-translational modification of proteins by catalyzing the addition of sialic acid residues to glycoproteins. Sialic acid is a negatively charged monosaccharide that is commonly found at the terminal positions of complex carbohydrates on the cell surface or secreted proteins.

   These enzymes belong to the family of glycosyltransferases, which are responsible for the transfer of sugar residues to various biomolecules. Glycoprotein sialyltransferases specifically transfer sialic acid to the glycan chains of glycoproteins. This process, known as sialylation, is essential for the proper functioning of glycoproteins and plays a critical role in various biological processes, including cell recognition, immune response, and cellular signaling.

   The glycoprotein sialyltransferases are classified into different subtypes based on their specificity for different glycan structures and linkage positions for sialic acid attachment. For example, some sialyltransferases preferentially transfer sialic acid to Galβ1-4GlcNAc (known as the N-acetyllactosamine structure), while others may exhibit different preferences or recognize distinct glycan structures.

   Deficiencies or abnormalities in glycoprotein sialyltransferases have been associated with several human diseases, including cancer, influenza infection, and autoimmune disorders. Therefore, these enzymes have become an important therapeutic target for the development of drugs and vaccines.

Common Misspellings for GLYCOPROTEIN SIALYLTRANSFERASES

• flycoprotein sialyltransferases
• vlycoprotein sialyltransferases
• blycoprotein sialyltransferases
• hlycoprotein sialyltransferases
• ylycoprotein sialyltransferases
• tlycoprotein sialyltransferases
• gkycoprotein sialyltransferases
• gpycoprotein sialyltransferases
• goycoprotein sialyltransferases
• gltcoprotein sialyltransferases
• glgcoprotein sialyltransferases
• glhcoprotein sialyltransferases
• glucoprotein sialyltransferases
• gl7coprotein sialyltransferases
• gl6coprotein sialyltransferases
• glyxoprotein sialyltransferases
• glyvoprotein sialyltransferases
• glyfoprotein sialyltransferases
• glydoprotein sialyltransferases
• glyciprotein sialyltransferases

Etymology of GLYCOPROTEIN SIALYLTRANSFERASES

The word "glycoprotein sialyltransferases" can be broken down into three main components: glycoprotein, sialyl, and transferases.

1. Glycoprotein: The term "glycoprotein" is composed of two parts - "glyco" from the Greek word "glykys" meaning "sweet" or "sugar", and "protein" which refers to any of a class of nitrogenous organic compounds composed of amino acids. Glycoproteins are proteins that have covalently attached carbohydrates, typically in the form of oligosaccharide chains.

2. Sialyl: The prefix "sialyl" is derived from "sialic acid". Sialic acid is a type of carbohydrate that is often found at the outermost ends of glycoprotein chains. It plays a role in cell recognition and immune responses.