How Do You Spell GLY TRNA LIGASE?

Pronunciation: [ɡlˈa͡ɪ tˈiː ˌɑːɹˌɛnˈe͡ɪ lˈɪɡe͡ɪs] (IPA)

The word "Gly tRNA Ligase" is a term from the field of biochemistry, referring to an enzyme which plays a crucial role in protein synthesis. Its spelling can be explained using the International Phonetic Alphabet (IPA), which represents each sound in words with specific symbols. "Gly" is pronounced as [ɡlaɪ], with a hard 'g' and a long 'i' sound. "tRNA" is pronounced as [tiː aɑr en eɪ], with an aspirated 't' and emphasis on the 'RNA' syllables. "Ligase" is pronounced as [laɪɡeɪs], with a long 'i' and emphasis on the 'ga' syllable.

GLY TRNA LIGASE Meaning and Definition

1. Gly tRNA Ligase, also known as glycyl-tRNA synthetase or GlyRS, is an enzyme involved in the process of protein synthesis. It plays a crucial role in the activation of glycine, an important amino acid, and its subsequent attachment to transfer RNA (tRNA) molecules in a process called aminoacylation.

   Gly tRNA Ligase belongs to the class of ligases, which are enzymes responsible for catalyzing the formation of chemical bonds. Specifically, this enzyme catalyzes the formation of a covalent bond between glycine and its corresponding tRNA molecule. This reaction requires the hydrolysis of ATP (adenosine triphosphate), providing the necessary energy for the process.

   The primary function of Gly tRNA Ligase is to ensure the accurate incorporation of glycine into growing peptide chains during translation. It achieves this by specifically recognizing the glycine molecule and attaching it to the correct tRNA molecule that recognizes the glycine codon on the messenger RNA (mRNA) template. This ensures that glycine is positioned correctly in the growing protein sequence, allowing for proper protein folding and function.

   Deficiencies or mutations in the Gly tRNA Ligase enzyme have been associated with certain human diseases, including Charcot-Marie-Tooth disease, a neurological disorder, and certain forms of muscular dystrophy. Understanding the structure and function of this enzyme provides important insights into the cellular mechanisms underlying protein synthesis and helps in the development of potential therapeutic strategies for related diseases.

Common Misspellings for GLY TRNA LIGASE

• fly trna ligase
• vly trna ligase
• bly trna ligase
• hly trna ligase
• yly trna ligase
• tly trna ligase
• gky trna ligase
• gpy trna ligase
• goy trna ligase
• glg trna ligase
• gl6 trna ligase
• gly rrna ligase
• gly frna ligase
• gly grna ligase
• gly yrna ligase
• gly 6rna ligase
• gly 5rna ligase
• gly tena ligase
• gly tdna ligase
• gly tfna ligase