How Do You Spell GERANYLGERANYL PYROPHOSPHATE SYNTHETASE?

Pronunciation: [d͡ʒˈɛɹɐnˌɪld͡ʒəɹˌana͡ɪl pˌa͡ɪɹə͡ʊfˈɒsfe͡ɪt sˈɪnθɪtˌe͡ɪs] (IPA)

The spelling of "Geranylgeranyl Pyrophosphate Synthetase" may seem daunting at first glance, but breaking it down into phonetic transcription can make it more manageable. The word begins with the "j" sound, represented in the IPA as /dʒ/. This is followed by the "eh" sound, represented as /ɛ/, and the "ran" sound, represented as /ræn/. The word also contains the "l" sound, represented by /l/, and the "ai" sound, represented as /aɪ/. The final part of the word, "Synthetase", contains the "th" sound, represented as /θ/, and the "ay" sound, represented as /eɪ/.

GERANYLGERANYL PYROPHOSPHATE SYNTHETASE Meaning and Definition

1. Geranylgeranyl pyrophosphate synthetase is an enzyme responsible for the synthesis of geranylgeranyl pyrophosphate (GGPP), an important molecule in various biological processes. It is an essential enzyme in the mevalonate pathway, a metabolic pathway involved in the synthesis of isoprenoids, a diverse group of natural products with critical functions in cellular processes.

   Geranylgeranyl pyrophosphate synthetase catalyzes the condensation of two molecules of isopentenyl pyrophosphate (IPP) with one molecule of dimethylallyl pyrophosphate (DMAPP). This reaction leads to the formation of geranylgeranyl pyrophosphate, a 20-carbon isoprenoid molecule. The enzyme is classified as a transferase, as it transfers the isopentyl and dimethylallyl groups from their respective pyrophosphate donors to form the long-chain geranylgeranyl pyrophosphate.

   The activity of geranylgeranyl pyrophosphate synthetase is crucial for the biosynthesis of a variety of essential molecules in cells, including carotenoids, chlorophylls, tocopherols, and important proteins involved in membrane targeting and protein prenylation. These molecules play vital roles in photosynthesis, antioxidant defense, and cellular signaling pathways.

   Inhibition or dysfunction of geranylgeranyl pyrophosphate synthetase can have significant consequences for cellular function and growth. Research on this enzyme is of great interest due to its potential as a therapeutic target for diseases related to isoprenoid metabolism and protein prenylation, such as some types of cancer and neurodegenerative disorders.

Common Misspellings for GERANYLGERANYL PYROPHOSPHATE SYNTHETASE

• feranylgeranyl pyrophosphate synthetase
• veranylgeranyl pyrophosphate synthetase
• beranylgeranyl pyrophosphate synthetase
• heranylgeranyl pyrophosphate synthetase
• yeranylgeranyl pyrophosphate synthetase
• teranylgeranyl pyrophosphate synthetase
• gwranylgeranyl pyrophosphate synthetase
• gsranylgeranyl pyrophosphate synthetase
• gdranylgeranyl pyrophosphate synthetase
• grranylgeranyl pyrophosphate synthetase
• g4ranylgeranyl pyrophosphate synthetase
• g3ranylgeranyl pyrophosphate synthetase
• geeanylgeranyl pyrophosphate synthetase
• gedanylgeranyl pyrophosphate synthetase
• gefanylgeranyl pyrophosphate synthetase
• getanylgeranyl pyrophosphate synthetase
• ge5anylgeranyl pyrophosphate synthetase
• ge4anylgeranyl pyrophosphate synthetase
• gerznylgeranyl pyrophosphate synthetase
• gersnylgeranyl pyrophosphate synthetase