GAMMAGLUTAMYLTRANSFERASE Meaning and
Definition
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Gammaglutamyltransferase, also known as GGT, is an enzyme that plays a crucial role in the metabolism of glutathione, an antioxidant that protects cells from oxidative damage. It is primarily found in the liver, but also exists in other organs such as the kidneys, pancreas, and intestines.
This enzyme is involved in the transfer of gamma-glutamyl groups between amino acids and peptides. By catalyzing the reaction, GGT aids in the breakdown and recycling of glutathione, as well as the metabolism of various components like amino acids and drugs.
In medical settings, GGT levels are measured through a blood test and can be an indicator of liver or bile duct dysfunction or damage. Increased levels of GGT are often associated with liver diseases such as hepatitis, cirrhosis, and liver cancer, as well as alcohol and drug abuse. It can also be elevated in conditions affecting the bile ducts, such as cholestasis or biliary obstruction.
Aside from its clinical significance, GGT has also been linked to other health conditions, including cardiovascular disease, diabetes, and kidney disease. Elevated GGT levels have been associated with an increased risk of developing these conditions.
In summary, gammaglutamyltransferase is an enzyme involved in the metabolism of glutathione and various other substances. Its levels in the blood can serve as a marker for liver and bile duct disorders, as well as other health conditions.
Common Misspellings for GAMMAGLUTAMYLTRANSFERASE
- fammaglutamyltransferase
- vammaglutamyltransferase
- bammaglutamyltransferase
- hammaglutamyltransferase
- yammaglutamyltransferase
- tammaglutamyltransferase
- gzmmaglutamyltransferase
- gsmmaglutamyltransferase
- gwmmaglutamyltransferase
- gqmmaglutamyltransferase
- ganmaglutamyltransferase
- gakmaglutamyltransferase
- gajmaglutamyltransferase
- gamnaglutamyltransferase
- gamkaglutamyltransferase
- gamjaglutamyltransferase
- gammzglutamyltransferase
- gammsglutamyltransferase
- gammwglutamyltransferase
- gammqglutamyltransferase
Etymology of GAMMAGLUTAMYLTRANSFERASE
The word "gammaglutamyltransferase" is derived from the combination of several elements:
1. Gamma: The term "gamma" comes from the Greek letter "γ" (gamma) and is used to represent the third letter of the Greek alphabet. In this context, "gamma" signifies the third position of the glutamyl molecule where the transferase enzyme acts.
2. Glutamyl: Derived from the amino acid "glutamic acid", the term "glutamyl" refers to the presence of a glutamyl group (–CH2CH2CONH–) within the molecule.
3. Transferase: This component of the word refers to the type of enzyme involved in transferring functional groups from one molecule to another. In this case, the enzyme is specifically involved in transferring the glutamyl group.
