GALLAMINE Meaning and
Definition
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Gallamine is a noun that refers to a non-depolarizing neuromuscular blocking agent used in medical procedures and surgeries to induce muscle relaxation. It is a synthetic compound derived from quaternary ammonium and is classified as a tertiary ammonium compound.
In the field of medicine, gallamine is primarily employed as a skeletal muscle relaxant, specifically in the context of surgical interventions where complete muscle relaxation is required. Its mechanism of action involves binding competitively to the nicotinic acetylcholine receptors found on the motor end plate of the neuromuscular junction. By doing so, gallamine prevents the binding of acetylcholine, an important neurotransmitter involved in muscle stimulation, leading to a temporary paralysis of the skeletal muscle.
The effects of gallamine administration typically become apparent within a few minutes after administration and can last for about 20 to 30 minutes, allowing surgeons to perform manipulations and procedures more effectively and efficiently. Following its use, gallamine is commonly reversed using other medications, such as neostigmine or edrophonium, which act to restore normal muscle function and strength.
Though gallamine can be effective in ensuring controlled relaxation of muscles during surgeries, its use is not without potential risks and side effects. Adverse reactions may include respiratory depression, hypotension, tachycardia, and allergic reactions. Therefore, its administration requires careful monitoring and should only be carried out by trained medical professionals in an appropriate clinical setting.
Common Misspellings for GALLAMINE
- fallamine
- vallamine
- ballamine
- hallamine
- yallamine
- tallamine
- gzllamine
- gsllamine
- gwllamine
- gqllamine
- gaklamine
- gaplamine
- gaolamine
- galkamine
- galpamine
- galoamine
- gallzmine
- gallsmine
- gallwmine
Etymology of GALLAMINE
The word "gallamine" is derived from the combination of two components: "gall" and "amine".
1. "Gall": The term "gall" originates from the Latin word "gallus", which means "oak nut" or "gallnut". Galls are abnormal outgrowths on various plants, such as oaks, caused by insects or microorganisms. These galls contain tannin, a substance often used traditionally for dyeing. The word "gall" has been adopted in pharmaceutical chemistry as a descriptor of certain alkaloids derived from gallic acid, a chemical compound found in galls.
2. "Amine": The term "amine" refers to a class of chemical compounds derived from ammonia (NH3) by replacing one or more hydrogen atoms with organic groups.
Similar spelling word for GALLAMINE
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