How Do You Spell ETRETINATE?

Pronunciation: [ɪtɹˈɛtɪnˌe͡ɪt] (IPA)

Etretinate is a medication used to treat severe psoriasis. Its spelling may appear daunting at first glance, but it can be explained using International Phonetic Alphabet (IPA) transcription. The first syllable is pronounced as "e-truh", with a schwa sound for the second vowel. The second syllable is pronounced "ti-tee". The third syllable is pronounced as "neyt", with a long A sound. The final syllable is pronounced "teen". Overall, the correct spelling of Etretinate is important to ensure efficient communication between healthcare professionals and patients.

ETRETINATE Meaning and Definition

1. Etretinate is a synthetic medication that belongs to the retinoid class of drugs and is used in the treatment of certain severe skin conditions. It is derived from acetic acid and is chemically related to vitamin A. Etretinate is mainly prescribed for patients suffering from psoriasis, a chronic autoimmune skin disorder characterized by thick, scaly patches on the skin.

   The primary mechanism of action of etretinate involves regulating the growth and differentiation of skin cells. It does so by binding to specific nuclear receptors, known as retinoic acid receptors, present in the nucleus of skin cells. By activating these receptors, etretinate modulates gene transcription, which ultimately restores normal skin cell production and reduces inflammation.

   Etretinate is usually administered orally in the form of a capsule or tablet. Due to its long half-life, etretinate has a cumulative effect, meaning it takes several weeks to achieve the desired therapeutic effect. Regular monitoring of liver function, blood lipid levels, and pregnancy tests is required during etretinate therapy due to potential side effects and teratogenicity (ability to cause birth defects).

   Etretinate should not be used in combination with other vitamin A derivatives or during pregnancy, as it can cause significant harm to the developing fetus. Due to its potential side effects, etretinate is typically prescribed as a last resort when other treatments have failed, and its use requires close monitoring by a healthcare professional.

Common Misspellings for ETRETINATE

• wtretinate
• stretinate
• dtretinate
• rtretinate
• 4tretinate
• 3tretinate
• erretinate
• efretinate
• egretinate
• eyretinate
• e6retinate
• e5retinate
• eteetinate
• etdetinate
• etfetinate
• ettetinate
• et5etinate
• et4etinate
• etrwtinate
• etrstinate

Etymology of ETRETINATE

The word "etretinate" comes from a combination of the chemical name "ethyl" and the suffix "-retin", which is derived from "retinoic acid". "Retinoic acid" is a derivative of vitamin A and is known for its role in regulating cell growth and differentiation. The addition of the prefix "et-" (which indicates the presence of an ethyl group) in front of "retinate" refers to the specific chemical structure of etretinate, which is an ethyl ester of retinoic acid.

Similar spelling word for ETRETINATE

• outreddened.