How Do You Spell EPOXIDE HYDROLASES?

Pronunciation: [ɪpˈɒksa͡ɪd hˈa͡ɪdɹəlˌe͡ɪsɪz] (IPA)

The word "Epoxide Hydrolases" is spelled phonetically as ɛpɒksaɪd haɪˈdrɒləsez. It is a type of enzyme that breaks down epoxides, which are reactive chemicals found in various substances. The first syllable, "epo-", indicates the type of chemical being targeted, while "oxide" refers to the specific functional group. "Hydrolases" indicates the type of enzyme involved in breaking down the compound. While the spelling of this word may seem confusing, its phonetic transcription clarifies its pronunciation and meaning.

EPOXIDE HYDROLASES Meaning and Definition

1. Epoxide hydrolases are a class of enzymes that catalyze the cleavage of epoxide rings, resulting in the formation of a vicinal diol. Epoxides are small, cyclic molecules containing a three-membered ring with an oxygen atom, which makes them highly reactive and toxic to cells. Consequently, epoxide hydrolases play a crucial role in the detoxification and metabolism of these compounds.

   The enzymatic reaction occurs through the addition of a water molecule to the epoxide ring, leading to the formation of a stable diol product. This reaction is facilitated by the enzyme's active site, which contains specific amino acid residues that stabilize the transition state and protonate the epoxide oxygen, promoting nucleophilic attack by water. The resulting vicinal diol can be further metabolized by other enzymes or excreted from the cell.

   Epoxide hydrolases are found in a wide range of organisms, including bacteria, plants, and animals. They exhibit high substrate specificity, with different isoforms of the enzyme being selective towards specific epoxides. This specificity allows the enzymes to act on a variety of toxic compounds, including environmental pollutants, drugs, and endogenous epoxides produced during cellular processes.

   Due to their detoxification capabilities, epoxide hydrolases have gained significant attention in biotechnology and pharmaceutical research. These enzymes have potential applications in drug metabolism, bioremediation, and the synthesis of valuable chemical compounds. Additionally, understanding the structure and function of epoxide hydrolases can provide insights into the mechanisms of enzyme catalysis and aid in the development of novel therapeutic strategies.

Common Misspellings for EPOXIDE HYDROLASES

• wpoxide hydrolases
• spoxide hydrolases
• dpoxide hydrolases
• rpoxide hydrolases
• 4poxide hydrolases
• 3poxide hydrolases
• eooxide hydrolases
• eloxide hydrolases
• e-oxide hydrolases
• e0oxide hydrolases
• epixide hydrolases
• epkxide hydrolases
• eplxide hydrolases
• eppxide hydrolases
• ep0xide hydrolases
• ep9xide hydrolases
• epozide hydrolases
• epocide hydrolases
• epodide hydrolases
• eposide hydrolases

Etymology of EPOXIDE HYDROLASES

The word "Epoxide Hydrolases" can be broken down into two components: "epoxide" and "hydrolases".

- "Epoxide" refers to a class of organic compounds that contain a three-membered ring consisting of two carbon atoms and one oxygen atom. This word is derived from the combination of the Greek prefix "epi" meaning "upon" or "above" and the root "oxide", referring to a compound containing oxygen.

- "Hydrolases" refers to a class of enzymes that catalyze the hydrolysis (a reaction involving the breaking of chemical bonds with water) of various chemical compounds. The term is derived from the combination of the word "hydro" meaning "water" and the suffix "-lases" indicating an enzyme.