Endo C Cytokeratin, also known as Endo Cytokeratin, is a specific type of cytokeratin protein found in the cells of various tissues in the human body. Cytokeratins are a group of intermediate filament proteins that play a crucial role in maintaining the structural integrity of cells, especially those present in epithelial tissues.
Endo C Cytokeratin is typically expressed in the cytoplasm and forms a part of the cellular framework known as the cytoskeleton. The cytoskeleton provides structural support to cells and is involved in cellular movement, shape determination, and intracellular transport.
Endo C Cytokeratin is widely used as a biomarker in scientific research and clinical diagnostics to identify and classify different types of epithelial cells. It is particularly useful in identifying carcinomas, which are malignant tumors that originate from epithelial cells.
The term "Endo Cytokeratin" refers specifically to a subclass of cytokeratins that are recognized and bound by a specific antibody called Anti-Endo C, hence the designation "Endo C." This antibody recognizes a particular epitope or region on the cytokeratin protein sequence.
The detection and measurement of Endo C Cytokeratin levels using techniques like immunohistochemistry and immunofluorescence can help in the diagnosis and characterization of various types of epithelial malignancies, including breast, prostate, lung, and gastrointestinal cancers. Additionally, it can also aid in studying the molecular mechanisms involved in the progression of these cancers and the development of potential targeted therapies.
