ECORI ENDONUCLEASE Meaning and
Definition
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EcoRI Endonuclease refers to a type II restriction enzyme derived from the bacterial species Escherichia coli (E. coli). The term "endonuclease" signifies an enzyme that specifically cleaves DNA at specific points within the molecule's sequence, usually recognized by a particular sequence of nucleotides known as a recognition site or restriction site.
EcoRI, also known as RY13 or EclRI, recognizes the specific six-base pair DNA sequence GAATTC, and it creates a staggered cut between the G and the A of this sequence. Since it cuts within the recognition site, it is classified as an endonuclease. The enzyme cleaves both DNA strands, resulting in single-stranded overhangs or sticky ends at the DNA ends.
EcoRI Endonuclease is commonly employed in molecular biology research and genetic engineering techniques. It is a crucial tool for DNA manipulation, such as gene cloning, DNA fragment analysis, and DNA sequence analysis. Its ability to precisely cut DNA at specific recognition sites allows researchers to insert foreign DNA into a plasmid or analyze specific regions of DNA. The sticky ends generated by EcoRI's cleavage enable the joining of DNA fragments with complementary single-stranded overhangs, facilitating the formation of recombinant DNA molecules.
Overall, EcoRI Endonuclease has been invaluable in various applications involving the manipulation of DNA due to its specificity in recognizing and cleaving DNA at precise locations, offering important advancements in genetic research and biotechnology.
Common Misspellings for ECORI ENDONUCLEASE
- wcori endonuclease
- scori endonuclease
- dcori endonuclease
- rcori endonuclease
- 4cori endonuclease
- 3cori endonuclease
- exori endonuclease
- evori endonuclease
- efori endonuclease
- edori endonuclease
- eciri endonuclease
- eckri endonuclease
- eclri endonuclease
- ecpri endonuclease
- ec0ri endonuclease
- ec9ri endonuclease
- ecoei endonuclease
- ecodi endonuclease
- ecofi endonuclease
- ecoti endonuclease
Etymology of ECORI ENDONUCLEASE
The word "EcoRI" comes from the name of the bacterium Escherichia coli (E. coli) strain RY13, which was the source of this particular endonuclease. The RY13 strain was isolated by its discoverers, Werner Arber and Daniel Nathans, in the mid-1960s. The "Eco" in EcoRI is derived from the first two letters of Escherichia coli, while the "R" represents the strain RY13. The "I" indicates that EcoRI was the first restriction enzyme isolated from this strain. Overall, "EcoRI Endonuclease" is named after the bacterial strain and the enzyme's function as an endonuclease, which cleaves DNA at specific recognition sites.
Similar spelling word for ECORI ENDONUCLEASE
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