DYSBETALIPOPROTEINEMIA Meaning and
Definition
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Dysbetalipoproteinemia is a rare genetic disorder characterized by abnormal lipid metabolism, leading to an accumulation of cholesterol and triglycerides in the bloodstream. It is also known as type III hyperlipoproteinemia or remnant removal disease.
In individuals with dysbetalipoproteinemia, the body is unable to properly process certain types of lipoproteins, namely beta-lipoprotein remnants. Normally, these remnants are cleared from the blood by the liver; however, in people with dysbetalipoproteinemia, this clearance mechanism is impaired. As a result, the remnants build up and contribute to elevated levels of cholesterol and triglycerides in the bloodstream.
The condition is typically inherited in an autosomal recessive manner, meaning that an affected individual must inherit two copies of the mutated gene, one from each parent. Symptoms of dysbetalipoproteinemia usually appear in adulthood and can include xanthomas (fatty deposits in the skin), yellowish discoloration of the skin and eyes (xanthelasma), pancreatic inflammation (pancreatitis), and cardiovascular problems such as atherosclerosis.
Diagnosing dysbetalipoproteinemia involves analyzing lipid profile tests and genetic testing. Treatment often involves lifestyle modifications, including a low-fat and low-cholesterol diet, regular exercise, and weight management. In more severe cases, medications such as statins or fibrates may be prescribed to help lower lipid levels. Treating any underlying conditions, such as diabetes or hypothyroidism, is also important. With proper management and lifestyle changes, individuals with dysbetalipoproteinemia can lead healthy lives and reduce the risk of complications.
Common Misspellings for DYSBETALIPOPROTEINEMIA
- sysbetalipoproteinemia
- xysbetalipoproteinemia
- cysbetalipoproteinemia
- fysbetalipoproteinemia
- rysbetalipoproteinemia
- eysbetalipoproteinemia
- dtsbetalipoproteinemia
- dgsbetalipoproteinemia
- dhsbetalipoproteinemia
- dusbetalipoproteinemia
- d7sbetalipoproteinemia
- d6sbetalipoproteinemia
- dyabetalipoproteinemia
- dyzbetalipoproteinemia
- dyxbetalipoproteinemia
- dydbetalipoproteinemia
- dyebetalipoproteinemia
- dywbetalipoproteinemia
- dysvetalipoproteinemia
- dysnetalipoproteinemia
Etymology of DYSBETALIPOPROTEINEMIA
The word "Dysbetalipoproteinemia" is a medical term referring to a rare genetic disorder characterized by abnormal lipid (fat) metabolism.
The etymology of this term consists of three parts:
1. "Dys-" is a prefix derived from the Greek word "dys", meaning "abnormal" or "difficult".
2. "Beta" refers to beta-lipoprotein, a type of lipoprotein that transports cholesterol and triglycerides (a type of fat) through the bloodstream.
3. "Proteinemia" is derived from two Greek roots: "proteino", meaning "protein", and "-emia", meaning "in the blood".
Thus, "Dysbetalipoproteinemia" can be understood as a compound word indicating an abnormal condition in which there are elevated levels of beta-lipoproteins and abnormal protein metabolism within the blood.
