DPPII Meaning and
Definition
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DPPII stands for Dual-Platelet Polymorphism 2, which is a gene polymorphism associated with increased platelet reactivity and risk of cardiovascular diseases. It refers to a specific genetic variation in the DP2 gene, also known as ITGA2B, which encodes for a protein called integrin alpha-IIb beta-3. This protein is found on the surface of platelets, the blood cells responsible for clotting.
The DPPII gene polymorphism is characterized by a variation in the DNA sequence that results in altered integrin alpha-IIb beta-3 functionality. This genetic variant is linked to an increase in platelet aggregability, meaning that platelets are more prone to clump together and form blood clots, potentially leading to the development of cardiovascular disorders such as heart attacks or strokes.
Individuals with the DPPII gene polymorphism may exhibit higher platelet activation and an increased tendency for their blood to clot, even in the absence of underlying risk factors. Consequently, they are at an elevated risk of developing conditions associated with abnormal clotting, such as deep vein thrombosis or arterial thrombosis.
Identifying DPPII genetic polymorphisms can be crucial in predicting an individual's risk of cardiovascular diseases, aiding in personalized preventive measures and clinical management. Genetic testing can be performed to determine the presence of this polymorphism, allowing healthcare professionals to understand a patient's genetic predisposition and implement appropriate interventions to mitigate the risk of cardiovascular events.
Common Misspellings for DPPII
- xppii
- fppii
- rppii
- dlpii
- d-pii
- d0pii
- dplii
- dp0ii
- dppui
- dppji
- dppoi
- dpp9i
- dpp8i
- dppiu
- dppik
- dppio
- dppi9
- dppi8
- sdppii
- dsppii
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