Diffuse Small Cleaved Cell Lymphoma is a rare type of non-Hodgkin lymphoma (NHL) that affects the lymphatic system, an integral part of the immune system. This condition is characterized by the abnormal growth and accumulation of cancerous cells in the lymph nodes and other lymphoid tissues in the body.
In this particular subtype of NHL, the cancer cells are described as small and cleaved. Small refers to their relatively small size compared to other lymphoma cells, while cleaved indicates that the cells have a distinct appearance and are divided into two symmetrical halves. These cells are usually characterized by their round or oval shape with abundant cytoplasm.
Diffuse Small Cleaved Cell Lymphoma typically presents with symptoms such as painless swelling of the lymph nodes, unexplained weight loss, fatigue, night sweats, and fever. However, the specific clinical presentation may vary between individuals.
Diagnosis of Diffuse Small Cleaved Cell Lymphoma involves a combination of physical examinations, blood tests, imaging studies (such as CT scans or PET-CT scans), and the analysis of lymph node biopsies. The exact cause of this lymphoma subtype is still unknown, but it is believed to result from genetic mutations that disrupt the normal functioning of lymphocytes, a type of white blood cell.
Treatment for Diffuse Small Cleaved Cell Lymphoma typically involves chemotherapy, radiation therapy, and in some cases, stem cell transplant. The prognosis for patients with this lymphoma subtype varies depending on various factors, including the stage and extent of the disease, the patient's overall health, and the response to treatment.
