DEIODINATION Meaning and
Definition
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Deiodination is a biological process that involves the removal of iodine from a molecule, particularly from the thyroid hormones known as thyroxine (T4) and triiodothyronine (T3). These hormones are produced by the thyroid gland and are essential for the regulation of various bodily functions, including metabolism, growth, and development.
In the process of deiodination, enzymes known as deiodinases catalyze the removal of iodine atoms from the hormone molecules. This enzymatic reaction occurs primarily in tissues such as the liver, kidneys, and intestines, as well as in target cells throughout the body. The deiodinases play a crucial role in controlling the balance and availability of active and inactive forms of thyroid hormones.
The removal of iodine can occur at specific positions on the hormone molecule, resulting in the formation of different compounds. For instance, the conversion of T4 to T3 involves the removal of one iodine atom, leading to the production of the more biologically active form of thyroid hormone. Additionally, deiodination can result in the generation of reverse T3 (rT3), an inactive form of the hormone.
Deiodination is a tightly regulated process, controlled by various factors, including hormonal signals and nutritional status. Dysregulation of deiodination can have significant consequences, as it can lead to alterations in the balance of thyroid hormones in the body, potentially resulting in metabolic disorders and other health issues.
In summary, deiodination is the enzymatic removal of iodine atoms from thyroid hormones, playing a critical role in regulating the availability and balance of these hormones throughout the body.
Common Misspellings for DEIODINATION
- seiodination
- xeiodination
- ceiodination
- feiodination
- reiodination
- eeiodination
- dwiodination
- dsiodination
- ddiodination
- driodination
- d4iodination
- d3iodination
- deuodination
- dejodination
- dekodination
- deoodination
- de9odination
- de8odination
- deiidination
- deikdination
Etymology of DEIODINATION
The word "deiodination" is composed of two parts: "deiodin" and "-ation".
The root of the word, "deiodin", comes from the term "iodin", which refers to iodine, a chemical element.
The suffix "-ation" means "the process or act of". In this case, it implies the process of something related to iodine.
Therefore, the word "deiodination" can be understood as the process of removing or reducing iodine from a certain substance or system.
